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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $293 | In Stock | |
5 mg | $533 | In Stock | |
10 mg | $683 | In Stock | |
25 mg | $928 | In Stock | |
50 mg | $1,260 | In Stock | |
100 mg | $1,680 | In Stock |
Description | CP 316311 is a specific CRF1 receptor antagonist with potential antidepressant activity and may be used in the study of depression. |
Targets&IC50 | CRF1 receptor:6.8 nM |
In vitro | CP-316311 is a CRF1 receptor antagonist that completely antagonizes CRF-stimulated adenylyl cyclase activity in rat cortex and endogenously expressed human CRF1 receptors in IMR32 cells[1]. |
In vivo | CP-316311 (3.2 mg/kg) demonstrates oral efficacy in central nervous system (CNS) models in vivo, blocking the effects of exogenous and endogenous CRF in rodent CNS models[1]. |
Molecular Weight | 327.46 |
Formula | C21H29NO2 |
Cas No. | 175139-41-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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