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Cinnamaldehyde

Catalog No. T4S1551   CAS 104-55-2
Synonyms: Cinnamic Aldehyde

1. Cinnamaldehyde (Cinnamic Aldehyde) has antipyretic activity. 2. Cinnamaldehyde is a sedative agent. 3. Cinnamaldehyde inhibits invasive capabilities of MDA-MB-435S cells was correlated with down-regulating the expression of miR-27a. 4. Cinnamaldehyde induces the generation of reactive oxygen species and exerts vasodilator and anticancer effects. 5. Cinnamaldehyde appears to be a promising candidate as an adjuvant in combination therapy with 5-fluorouracil (5-FU) and oxaliplatin (OXA), two chemotherapeutic agents used in CRC treatment. The possible mechanisms of its action may involve the regulation of drugmetabolizing genes. 6. Cinnamaldehyde plays a certain role in inhibiting the occurrence and progression of melanoma and its action mechanism may be manifested by inhibiting expression of VEGF and HIF-α, thus blood vessel simulation and formation of new blood vessels of melanoma cells, and growth of tumors accordingly.

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Cinnamaldehyde Chemical Structure
Cinnamaldehyde, CAS 104-55-2
Pack Size Availability Price/USD Quantity
100 mg In stock $ 30.00
500 mg In stock $ 64.00
1 g In stock $ 93.00
1 mL * 10 mM (in DMSO) In stock $ 39.00
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Purity: 85%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description 1. Cinnamaldehyde (Cinnamic Aldehyde) has antipyretic activity. 2. Cinnamaldehyde is a sedative agent. 3. Cinnamaldehyde inhibits invasive capabilities of MDA-MB-435S cells was correlated with down-regulating the expression of miR-27a. 4. Cinnamaldehyde induces the generation of reactive oxygen species and exerts vasodilator and anticancer effects. 5. Cinnamaldehyde appears to be a promising candidate as an adjuvant in combination therapy with 5-fluorouracil (5-FU) and oxaliplatin (OXA), two chemotherapeutic agents used in CRC treatment. The possible mechanisms of its action may involve the regulation of drugmetabolizing genes. 6. Cinnamaldehyde plays a certain role in inhibiting the occurrence and progression of melanoma and its action mechanism may be manifested by inhibiting expression of VEGF and HIF-α, thus blood vessel simulation and formation of new blood vessels of melanoma cells, and growth of tumors accordingly.
Source
Synonyms Cinnamic Aldehyde
Molecular Weight 132.16
Formula C9H8O
CAS No. 104-55-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 45 mg/mL (340.49 mM)

TargetMolReferences and Literature

1. Raffai, Gábor, Kim B , Park S , et al. Cinnamaldehyde and cinnamaldehyde-containing micelles induce relaxation of isolated porcine coronary arteries: role of nitric oxide and calcium[J]. International Journal of Nanomedicine, 2014.

TargetMolCitations

1. Cao L, Xu E, Zheng R, et al. Traditional Chinese medicine Lingguizhugan decoction ameliorate HFD-induced hepatic-lipid deposition in mice by inhibiting STING-mediated inflammation in macrophages. Chinese Medicine. 2022, 17(1): 1-16.

Related compound libraries

This product is contained In the following compound libraries:
Inhibitor Library Tobacco Monomer Library Anti-Cancer Active Compound Library Food Additive Library HIF-1 Signaling Pathway Compound Library Natural Product Library Bioactive Compounds Library Max Natural Product Library for HTS Bioactive Compound Library Epigenetics Compound Library

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Keywords

Cinnamaldehyde 104-55-2 Angiogenesis Chromatin/Epigenetic HIF Cinnamic Aldehyde inhibitor inhibit

 

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