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Ferruginol

Catalog No. TN1642 CAS 514-62-5

Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic, cardioprotective, anticancer, anti-oxidative and anti-inflammatory activities, it can induce apoptosis in non-small cell lung cancer (NSCLC) cells.

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Ferruginol, CAS 514-62-5

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5 mg	Inquiry	$ 460.00
1 mL * 10 mM (in DMSO)	Inquiry	$ 470.00

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Description	Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic, cardioprotective, anticancer, anti-oxidative and anti-inflammatory activities, it can induce apoptosis in non-small cell lung cancer (NSCLC) cells.
In vitro	The radial accumulation pattern of Ferruginol was examined from sapwood and through the intermediate wood to the heartwood by direct mapping using time-of-flight secondary ion mass spectrometry (TOF-SIMS). The data were compared with quantitative results obtained from a novel method of gas chromatography analysis using laser microdissection sampling and with water distribution obtained from cryo-scanning electron microscopy. Ferruginol initially accumulated in the middle of the intermediate wood, in the earlywood near the annual ring boundary. It accumulated throughout the entire earlywood in the inner intermediate wood, and in both the earlywood and the latewood in the heartwood. The process of Ferruginol accumulation continued for more than eight annual rings. Ferruginol concentration peaked at the border between the intermediate wood and heartwood, while the concentration was less in the latewood compared with the earlywood in each annual ring. Ferruginol tended to accumulate around the ray parenchyma cells. In addition, at the border between the intermediate wood and heartwood, the accumulation was higher in areas without water than in areas with water[1]
Source	Natural Products > Lamiaceae > Salvia

Molecular Weight	286.459
Formula	C20H30O
CAS No.	514-62-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. The accumulation pattern of ferruginol in the heartwood-forming Cryptomeria japonica xylem as determined by time-of-flight secondary ion mass spectrometry and quantity analysis.Ann Bot. 2014 May;113(6):1029-36.

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Keywords

Ferruginol 514-62-5 Apoptosis Chromatin/Epigenetic DNA Damage/DNA Repair Proteases/Proteasome Caspase BCL PARP inhibitor inhibit

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