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Florfenicol
Florfenicol (SCH-25298), a fluorinated synthetic analog of thiamphenicol, is currently indicated for the therapy of bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) haemolytica, Haemophilus somnus, and Pasteurella multocida, for therapy of bovine interdigital phlegmon (foot rot, infectious pododermatitis, acute interdigital necrobacillosis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus. This compound is also used in aquaculture and is approved for use in the United States for the therapy of enteric septicemia in catfish.
Catalog No. T0454LCas No. 73231-34-2
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Purity:99%
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Florfenicol
Catalog No. T0454LCas No. 73231-34-2
Florfenicol (SCH-25298), a fluorinated synthetic analog of thiamphenicol, is currently indicated for the therapy of bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) haemolytica, Haemophilus somnus, and Pasteurella multocida, for therapy of bovine interdigital phlegmon (foot rot, infectious pododermatitis, acute interdigital necrobacillosis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus. This compound is also used in aquaculture and is approved for use in the United States for the therapy of enteric septicemia in catfish.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 500 mg | $47 | In Stock | |
| 1 g | $68 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $29 | In Stock |
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CitedProduct Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Florfenicol (SCH-25298), a fluorinated synthetic analog of thiamphenicol, is currently indicated for the therapy of bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) haemolytica, Haemophilus somnus, and Pasteurella multocida, for therapy of bovine interdigital phlegmon (foot rot, infectious pododermatitis, acute interdigital necrobacillosis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus. This compound is also used in aquaculture and is approved for use in the United States for the therapy of enteric septicemia in catfish. |
| In vitro | Florfenicol is found to stimulate algal growth at concentrations of 0.5, 1.0 and 2.0 mg/L, and significantly inhibit algal growth at >2.0 mg/L. |
| In vivo | Florfenicol administers at doses of 15 and 20 mg FFC kg(-1) bw per days for 10 days significantly reduces mortality associated with francisellosis in Nile tilapia. |
| Alias | SCH-25298, (-)-Florfenicol |
| Molecular Weight | 358.21 |
| Formula | C12H14Cl2FNO4S |
| Cas No. | 73231-34-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (139.58 mM), Sonication is recommended.  Ethanol: 8 mg/mL (22.33 mM) H2O: < 1 mg/mL (insoluble or slightly soluble) | ||||||||||||||||||||||||||||||||||||||||
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Ethanol/DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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