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Fluorizoline
🥰Excellent
Catalog No. T31821Cas No. 1362243-70-6
Fluorizoline is a PHB-binding compound with anticancer and antiproliferative activity that induces apoptosis by inducing selective targeting of the BH3 protein NOXA to PHB.Fluorizoline inhibits protein synthesis and has been used in studies of leukemia.
Fluorizoline
🥰Excellent
Purity: 99.52%
Catalog No. T31821Cas No. 1362243-70-6
Fluorizoline is a PHB-binding compound with anticancer and antiproliferative activity that induces apoptosis by inducing selective targeting of the BH3 protein NOXA to PHB.Fluorizoline inhibits protein synthesis and has been used in studies of leukemia.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $58 | In Stock |
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Purity:99.52%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Fluorizoline is a PHB-binding compound with anticancer and antiproliferative activity that induces apoptosis by inducing selective targeting of the BH3 protein NOXA to PHB.Fluorizoline inhibits protein synthesis and has been used in studies of leukemia. |
| In vitro | In primary CLL cells, Fluorizoline (1.25 to 20 μM; 24 hours) significantly reduced cell viability and induced apoptosis in a dose-dependent manner[1]. |
| Molecular Weight | 362.20 |
| Formula | C15H8Cl2F3NS |
| Cas No. | 1362243-70-6 |
| Smiles | FC1(F)N=C(SC1(F)c1ccc(Cl)cc1)c1ccc(Cl)cc1 |
| Relative Density. | 1.47 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 30 mg/mL (82.83 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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