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Hirsutanonol
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Catalog No. TN4212Cas No. 41137-86-4
Hirsutanonol is a secondary metabolite from the bark of Alnus glutinosa. Hirsutanonol has potent antioxidant and free radical scavenging activities and exhibits an inhibition effect on mitochondrial lipid peroxidation. Hirsutanonol can be used for studies
Hirsutanonol
😃Good
Catalog No. TN4212Cas No. 41137-86-4
Hirsutanonol is a secondary metabolite from the bark of Alnus glutinosa. Hirsutanonol has potent antioxidant and free radical scavenging activities and exhibits an inhibition effect on mitochondrial lipid peroxidation. Hirsutanonol can be used for studies
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 631 € | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Hirsutanonol is a secondary metabolite from the bark of Alnus glutinosa. Hirsutanonol has potent antioxidant and free radical scavenging activities and exhibits an inhibition effect on mitochondrial lipid peroxidation. Hirsutanonol can be used for studies |
| In vitro | Hirsutanonol shows significant inhibitory effects on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced cyclooxygenase-2 (COX-2) expression in immortalized human breast epithelial MCF10A cells. Hirustenone and hirsutanonol show promising anti-filarial activity both in vitro and in vivo studies.Hirsutanonol shows potent cytotoxic activities against murine B16 melanoma cells and human SNU-C1 gastric cancer cells, it also has a chemoprotective effect on human lymphocyte DNA. Hirsutanonol (1 µg/mL) decreased the frequency of micronuclei by 63.6 %, exerting a much stronger effect than the synthetic protector amifostine (17.2 %, 1 µg/mL)[1]. |
| Molecular Weight | 346.37 |
| Formula | C19H22O6 |
| Cas No. | 41137-86-4 |
| Smiles | OC(CCc(cc1)cc(O)c1O)CC(CCc(cc1)cc(O)c1O)=O |
| Relative Density. | 1.362 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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