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IRAK inhibitor 4 trans

IRAK inhibitor 4 trans
IRAK inhibitor 4 is a compound that functions as an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4). It specifically targets and inhibits the activity of IRAK4. The (trans) form of IRAK inhibitor 4 refers to its specific molecular configuration.
Catalog No. T11671

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IRAK inhibitor 4 trans

Catalog No. T11671

IRAK inhibitor 4 is a compound that functions as an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4). It specifically targets and inhibits the activity of IRAK4. The (trans) form of IRAK inhibitor 4 refers to its specific molecular configuration.
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Pack SizePriceAvailabilityQuantity
2 mg$396Backorder
5 mg$593Backorder
10 mgInquiryBackorder
50 mgInquiryBackorder
1 mL x 10 mM (in DMSO)$808Backorder
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Product Introduction

Bioactivity
Description
IRAK inhibitor 4 is a compound that functions as an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4). It specifically targets and inhibits the activity of IRAK4. The (trans) form of IRAK inhibitor 4 refers to its specific molecular configuration.
Chemical Properties
Molecular Weight620.66
FormulaC33H35F3N6O3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 38 mg/mL (61.23 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6112 mL8.0559 mL16.1119 mL80.5594 mL
5 mM0.3222 mL1.6112 mL3.2224 mL16.1119 mL
10 mM0.1611 mL0.8056 mL1.6112 mL8.0559 mL
20 mM0.0806 mL0.4028 mL0.8056 mL4.0280 mL
50 mM0.0322 mL0.1611 mL0.3222 mL1.6112 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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