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Iganidipine

Catalog No. T15553   CAS 119687-33-1
Synonyms: NKY 722

Iganidipine(NKY 722) is a new water-soluble Ca2+ antagonist with antihypertensive activity for research and neurological related diseases.

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Iganidipine Chemical Structure
Iganidipine, CAS 119687-33-1
Pack Size Availability Price/USD Quantity
1 mg In stock $ 700.00
5 mg In stock $ 1,800.00
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Purity: 96.85%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Iganidipine(NKY 722) is a new water-soluble Ca2+ antagonist with antihypertensive activity for research and neurological related diseases.
In vivo After a single administration, Iganidipine (0.03% solution) significantly increases optic nerve head (ONH) tissue blood velocity (NBONH) by 8 to 10% in treated eyes (p<0.05). Additionally, following twice-daily administration for 7, 14, or 21 days in rabbits, it results in a significant increase of 18 to 35% in NBONH (p<0.05). In monkeys, after 7 days of twice-daily administration, both 0.03% and 0.1% Iganidipine significantly increase NBONH in treated eyes by 20% and 41%, respectively (p<0.05)[1].
Synonyms NKY 722
Molecular Weight 526.62
Formula C28H38N4O6
CAS No. 119687-33-1

Storage

store at low temperature

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Ishii K, et al. Iganidipine, a new water-soluble Ca2+ antagonist: ocular and periocular penetration after instillation. Invest Ophthalmol Vis Sci. 2003 Mar;44(3):1169-77.

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Keywords

Iganidipine 119687-33-1 Membrane transporter/Ion channel Metabolism Calcium Channel NKY 722 inhibitor inhibit

 

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