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Imipenem monohydrate (Imipenem) is a carbapenem antibiotic isolated from the microorganism Streptomyces cattleya, and is a β lactam antibiotic. Imipenem monohydrate acts on the bacterial cell wall, and is a broadly effective inhibitor of a wide range of Gram-positive and negative bacteria.
Pack Size | Price | Availability | Quantity |
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100 mg | $53 | In Stock | |
200 mg | $79 | In Stock |
Description | Imipenem monohydrate (Imipenem) is a carbapenem antibiotic isolated from the microorganism Streptomyces cattleya, and is a β lactam antibiotic. Imipenem monohydrate acts on the bacterial cell wall, and is a broadly effective inhibitor of a wide range of Gram-positive and negative bacteria. |
In vivo | METHODS: To study the effect on tuberculosis, Imipenem monohydrate (100 mg/kg) was administered subcutaneously to a mouse model of tuberculosis twice daily for 28 days. RESULTS: Imipenem significantly reduced the number of Mycobacterium tuberculosis in the lungs and spleens, and increased the survival rate of the mice. [1] METHODS: To assess the effect on the kinetics of the inflammatory response in a mouse model of sepsis, Imipenem monohydrate (25-125 mg/kg) was administered subcutaneously to CLP-induced septic mice once daily for three days. RESULTS: Subcutaneous injection of Imipenem had a dose-dependent effect on the inflammatory response in septic mice. In septic mice, the 25 mg/kg dose of Imipenem resulted in better pathology, lower inflammatory mediators and improved survival. [2] |
Alias | N-Formimidoyl thienamycin monohydrate, Imipenem |
Molecular Weight | 317.36 |
Formula | C12H19N3O5S |
Cas No. | 74431-23-5 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | H2O: 6.67 mg/mL (21.02 mM; Need ultrasonic) DMSO: < 1 mg/mL (insoluble or slightly soluble) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
H2O
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