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LSN2463359

🥰Excellent
Catalog No. T27854Cas No. 1401031-52-4
Alias LSN-2463359, LSN 2463359

LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.

LSN2463359

LSN2463359

🥰Excellent
Purity: 99.36%
Catalog No. T27854Alias LSN-2463359, LSN 2463359Cas No. 1401031-52-4
LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.
Pack SizePriceAvailabilityQuantity
2 mg$30In Stock
5 mg$48In Stock
10 mg$77In Stock
25 mg$173In Stock
50 mg$273In Stock
100 mg$403In Stock
200 mg$573In Stock
1 mL x 10 mM (in DMSO)$53In Stock
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Purity:99.36%
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Product Introduction

Bioactivity
Description
LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.
AliasLSN-2463359, LSN 2463359
Chemical Properties
Molecular Weight265.31
FormulaC16H15N3O
Cas No.1401031-52-4
SmilesCC(C)NC(=O)c1ccc(cn1)C#Cc1ccncc1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 112.5 mg/mL (424.0 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7692 mL18.8459 mL37.6918 mL188.4588 mL
5 mM0.7538 mL3.7692 mL7.5384 mL37.6918 mL
10 mM0.3769 mL1.8846 mL3.7692 mL18.8459 mL
20 mM0.1885 mL0.9423 mL1.8846 mL9.4229 mL
50 mM0.0754 mL0.3769 mL0.7538 mL3.7692 mL
100 mM0.0377 mL0.1885 mL0.3769 mL1.8846 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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