Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Lucidenic acid C has anti-invasive effect, it shows significant inhibitory effects on PMA-induced MMP-9 activity and invasion of HepG(2 )cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | Inquiry | $ 350.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 250.00 |
Description | Lucidenic acid C has anti-invasive effect, it shows significant inhibitory effects on PMA-induced MMP-9 activity and invasion of HepG(2 )cells. |
In vitro | Triterpenoid components in the ethanol extract of G. lucidum (YK-02) were separated by means of a semi-preparative RP HPLC. Four major peaks were separated and crystallized from triterpenoids fraction, and were identified as lucidenic acid A, lucidenic acid B, Lucidenic acid C, and lucidenic acid N according to their spectroscopic values of (1)H NMR and MS. Treatment of the lucidenic acids (50 microM) in the presence of 200 nM phorbol 12-myristate 13-acetate (PMA) after 24 h of incubation all resulted in significant inhibitory effects on PMA-induced MMP-9 activity and invasion of HepG(2 )cells. |
Molecular Weight | 476.6 |
Formula | C27H40O7 |
CAS No. | 95311-96-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Lucidenic acid C 95311-96-9 Proteases/Proteasome MMP inhibitor inhibit