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MRS1845 is an ORAI1 inhibitor and calcium entry (SOCE) blocker that blocks VP-induced SOCE, OS, and Ca(2+) deposition.
Pack Size | Price | Availability | Quantity |
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1 mg | $48 | In Stock | |
5 mg | Inquiry | In Stock |
Description | MRS1845 is an ORAI1 inhibitor and calcium entry (SOCE) blocker that blocks VP-induced SOCE, OS, and Ca(2+) deposition. |
In vitro | Additional treatment with the ORAI1 inhibitor MRS1845 (10 μM) actually disrupted the effect of β-glycerophosphate on SOCE. Furthermore, in the presence of the ORAI1 inhibitor and when ORAI1 was silenced, the expression and activity of β-glycerophosphate-induced MSX2, CBFA1, SOX9, and ALPL mRNA in HAoSMCs were inhibited[2]. |
Molecular Weight | 398.41 |
Formula | C21H22N2O6 |
Cas No. | 544478-19-5 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | H2O: < 0.1 mg/mL (insoluble) DMSO: 60 mg/mL (150.60 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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