Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Naphthol AS-E

Naphthol AS-E
Naphthol AS-E (nAS-E) is an the KIX-KID interaction and CREB-mediated gene transcription inhibitor.
Catalog No. T7856Cas No. 92-78-4
Select Batch
Purity:99.33%
Contact us for more batch information
Resource Download

Naphthol AS-E

Catalog No. T7856Cas No. 92-78-4
Naphthol AS-E (nAS-E) is an the KIX-KID interaction and CREB-mediated gene transcription inhibitor.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
100 mg$30In Stock
500 mg$67In Stock
1 g$98In Stock
1 mL x 10 mM (in DMSO)$31In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "Naphthol AS-E"

Product Introduction

Bioactivity
Description
Naphthol AS-E (nAS-E) is an the KIX-KID interaction and CREB-mediated gene transcription inhibitor.
Targets&IC50
c-Kit:2.26 μM (IC50)
In vivo
nAS-E could reverse bone loss induced by MDA-MB-231 tumour.?These results suggest that small molecules targeting CREB-CBP interaction to inhibit CREB-mediated gene transcription might be a potential approach for the treatment of breast cancer bone metastasis[1].
AliasnAS-E
Chemical Properties
Molecular Weight297.74
FormulaC17H12ClNO2
Cas No.92-78-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 2.98 mg/mL (10 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3586 mL16.7932 mL33.5864 mL167.9318 mL
5 mM0.6717 mL3.3586 mL6.7173 mL33.5864 mL
10 mM0.3359 mL1.6793 mL3.3586 mL16.7932 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Naphthol AS-E | purchase Naphthol AS-E | Naphthol AS-E cost | order Naphthol AS-E | Naphthol AS-E chemical structure | Naphthol AS-E in vivo | Naphthol AS-E formula | Naphthol AS-E molecular weight