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Niraparib metabolite M1

Name: Niraparib metabolite M1
Brand: TargetMol
SKU: T12229
Price: 44 USD
Availability: InStock
Rating: 4.5 (1 reviews)

Catalog No. T12229Cas No. 1476777-06-6

Alias Niraparib carboxylic acid metabolite M1, M1 metabolite of niraparib

Niraparib metabolite M1 is niraparib metabolite, niraparib is a novel poly(ADP-Ribose) polymerase (PARP) inhibitor.

Niraparib metabolite M1

Catalog No. T12229Alias Niraparib carboxylic acid metabolite M1, M1 metabolite of niraparibCas No. 1476777-06-6

Niraparib metabolite M1 is niraparib metabolite, niraparib is a novel poly(ADP-Ribose) polymerase (PARP) inhibitor.

Pack Size	Price	Availability
25 mg	$1,350	6-8 weeks
50 mg	$1,760	6-8 weeks
100 mg	$2,500	6-8 weeks

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Product Introduction

Bioactivity

Description	Niraparib metabolite M1 is niraparib metabolite, niraparib is a novel poly(ADP-Ribose) polymerase (PARP) inhibitor.
Alias	Niraparib carboxylic acid metabolite M1, M1 metabolite of niraparib

Chemical Properties

Molecular Weight	321.37
Formula	C₁₉H₁₉N₃O₂
Cas No.	1476777-06-6

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 100 mg/mL (311.17 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1117 mL	15.5584 mL	31.1168 mL	155.5839 mL
5 mM	0.6223 mL	3.1117 mL	6.2234 mL	31.1168 mL
10 mM	0.3112 mL	1.5558 mL	3.1117 mL	15.5584 mL
20 mM	0.1556 mL	0.7779 mL	1.5558 mL	7.7792 mL
50 mM	0.0622 mL	0.3112 mL	0.6223 mL	3.1117 mL
100 mM	0.0311 mL	0.1556 mL	0.3112 mL	1.5558 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Niraparib metabolite M1Niraparib metabolite M-1