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Norharmane

Catalog No. T4024 CAS 244-63-3

Synonyms: 2-Azacarbazole, 去甲哈尔满, 2,9-Diazafluorene, β-Carboline

Norharmane is a natural β-carboline first isolated from plants of the Zygophyllaceae family.

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Norharmane, CAS 244-63-3

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Norharmane is a natural β-carboline first isolated from plants of the Zygophyllaceae family.
Targets&IC50	MAO-A:3.34 μM (Ki)

Synonyms	2-Azacarbazole, 去甲哈尔满, 2,9-Diazafluorene, β-Carboline
Molecular Weight	168.199
Formula	C11H8N2
CAS No.	244-63-3

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 10 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Jamali., et al. Inhibitory effect of Rosa rugosa tea extract on the formation of heterocyclic amines in meat patties at different temperatures. Molecules 21(2), 173 (2016). 2. Smith, T.T.,Schaff, M.B.,Rupprecht, L.E., et al. Effects of MAO inhibition and a combination of minor alkaloids, β-carbolines, and acetaldehyde on nicotine self-administration in adult male rats. Drug Alcohol Depend. 2015:155, 243-252 (2015).

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library Anti-Lung Cancer Compound Library Inhibitor Library DNA Damage & Repair Compound Library Target-Focused Phenotypic Screening Library Anti-Aging Compound Library Bioactive Compound Library

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Related compounds with same targets

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Dose Conversion

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Norharmane 244-63-3 DNA损伤和修复代谢神经科学 DNA Endogenous Metabolite Monoamine Oxidase Monoamine Coffee MAO β-Carboline disease Parkinson Alkaloid inhibit Norharman 2,9-Diazafluorene oxidase 2-Azacarbazole Neuroprotection Inhibitor inhibitor

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