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Cat No. | Product Name | Synonyms | Targets |
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T10509 | Xanthine oxidase-IN-1 | 4-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid | Xanthine Oxidase |
Xanthine oxidase-IN-1 is an effective inhibitor of xanthine oxidase with an IC50 value of 6.5 nM. It plays a central role in purine catabolism through the degradation of bioactive nucleotides facilitated by nucleic acid ... | |||
T76148 | Glucose oxidase | Endogenous Metabolite | |
Glucose oxidase, an enzyme extracted from the fungus Aspergillus niger, is an important industrial enzyme in the food industry and is widely used in the deoxygenation of foods such as wine, beer, fruit juice, milk powder... | |||
T78984 | Xanthine oxidase-IN-10 | XO8 analog | ROS |
Xanthine oxidase-IN-10 (XO8 analog) is a xanthine oxidase (XO) inhibitor for the study of gout. | |||
T76104 | Xanthine oxidase | ||
Xanthine oxidase, a xanthine oxidoreductase enzyme, catalyzes the oxidation of hypoxanthine to xanthine and further oxidizes xanthine to uric acid, generating reactive oxygen species (ROS) [1]. | |||
T11429 | Glycolic acid oxidase inhibitor 1 | Others | |
Glycolic acid oxidase inhibitor 1 is a glycolate oxidase inhibitor. | |||
T76143 | Pyruvate oxidase | ||
Pyruvate oxidase (PoxB), a thiamine pyrophosphate-dependent enzyme, performs the oxidative decarboxylation of pyruvate to acetyl phosphate, carbon dioxide, and water. This enzyme plays a crucial role in bacterial metabol... | |||
T76105 | Alcohol oxidase | ||
Alcohol oxidase, a key enzyme in the methanol utilization pathway, is derived from yeast peroxisomes. | |||
T76101 | Ascorbate oxidase | ||
Ascorbate oxidase, or Vitamin C oxidase, is a redox (REDOX) enzyme that plays a crucial role in extracellular matrix regulation by catalyzing the oxidation of ascorbic acid to dehydroascorbic acid in the presence of oxyg... | |||
T76150 | Galactose oxidase | ||
Galactose oxidase (GOase), a type II copper metalloenzyme derived from fungus, comprises a single polypeptide. It is commonly utilized in biochemical studies for catalyzing the two-electron oxidation of primary alcohols ... | |||
T76141 | Bilirubin oxidase | ||
Bilirubin oxidase (BOD), a multi-copper oxidase, catalyzes the transformation of bilirubin into biliverdin while reducing molecular oxygen to water. This enzyme plays a role in porphyrin and chlorophyll metabolism and is... | |||
T78358 | Choline oxidase | ||
Choline oxidase is an enzyme that facilitates the conversion of choline to glycine betaine through an intermediate, betaine aldehyde, during the synthesis of glycine betaine. Glycine betaine serves as an osmolyte. Furthe... | |||
T73617 | Urate oxidase | ||
Urate oxidase (Uox), also known as uricase, is a peroxisomal enzyme widely utilized in biochemical research. It catalyzes the conversion of uric acid to allantoin in the majority of mammals [1]. | |||
T75422 | Monoamine oxidase | ||
Monoamine oxidase, an enzyme comprising various polypeptides, catalyzes the oxidative deamination of diverse biological amines within both brain and peripheral tissues, yielding hydrogen peroxide in the process. This enz... | |||
T76131 | Sarcosine oxidase | ||
Sarcosine oxidase (SAO) catalyzes the oxidative demethylation of sarcosine, producing glycine, H2O2, and 5,10-CH2-tetrahydrofolate, substances commonly utilized in biochemical reactions [1]. | |||
T78348 | Lactate oxidase | ||
Lactate oxidase, an FMN-dependent enzyme, catalyzes the conversion of lactate to pyruvate while releasing hydrogen peroxide and is utilized in the detection of lactate [1]. | |||
T76128 | Cholesterol oxidase | ||
Cholesterol oxidase (ChOx), a bacterial flavin oxidase containing FAD utilized in biochemical research, catalyzes the oxidation of the C(3)-OH group of cholesterol (and other sterols) to cholest-5-en-3-one and subsequent... | |||
T61092 | Xanthine oxidase-IN-5 | ||
Xanthine oxidase-IN-5, a powerful and orally active inhibitor of xanthine oxidase (XO), exhibits an IC50 value of 0.70 μM. It possesses favorable drug-like characteristics, with ligand efficiency (LE) and lipophilic liga... | |||
T72409 | Xanthine oxidase-IN-6 | ||
Xanthine oxidase-IN-6, a potent and orally active mixed-type inhibitor of xanthine oxidase (XOD), demonstrates significant anti-hyperuricemia and renal protective activity with an IC50 value of 1.37 µM. | |||
T60632 | Xanthine oxidase-IN-4 | ||
Xanthine oxidase-IN-4 (compound 19a) is an orally active and potent inhibitor of xanthine oxidase(XO) with an IC 50 of 0.039 μM that can be used in the research of hyperuricemia and gout. Xanthine oxidase-IN-4 shows hypo... | |||
T76170 | D-Amino acid oxidase | ||
D-Amino acid oxidase, an enzyme that metabolizes exogenous D-amino acids in animals for detoxification, also regulates the level of D-serine in the brain [1]. | |||
T60626 | Xanthine oxidase-IN-7 | ||
Xanthine oxidase-IN-7 (compound1h) is a potent andorally active xanthine oxidase(XO) inhibitor (IC50 = 0.36 μM). Xanthine oxidase-IN-7 effectively reduces serum uric acid levels which has the potential in the hyperuricem... | |||
T78985 | Xanthine oxidase-IN-11 | Xanthine Oxidase | |
Xanthine Oxidase-IN-11, an analog of XO8, is an inhibitor of xanthine oxidase (XO) [1]. | |||
T80767 | Xanthine oxidase-IN-12 | Xanthine Oxidase | |
Xanthine oxidase-IN-12 (Compound 11), an inhibitor of xanthine oxidase (XO), possesses an IC50 value of 91 nM and exhibits antioxidant properties, additionally diminishing intracellular reactive oxygen species (ROS) [1]. | |||
T76098 | Glycerol-3-phosphate oxidase | ||
Glycerol-3-phosphate oxidase, a crucial intermediate in glycerol metabolism, can be extracted from Escherichia coli. It serves as the backbone for phospholipids in membrane lipids and acts as a substrate in the respirato... | |||
T78356 | Fructosyl amino acid oxidase | ||
Fructosyl amino acid oxidase is utilized for the quantification of glycosylated proteins, particularly glycosylated hemoglobin A1c, which serves as a critical biomarker for assessing diabetes treatment efficacy [1]. | |||
T82289 | Glycolate oxidase-IN-1 | ||
Glycolate oxidase-IN-1 (compound 26), a salicylic acid derivative, serves as an inhibitor of glycolate oxidase (GO) and exhibits an inhibitory concentration (IC50) of 38.2 μM. It is efficacious in reducing oxalate produc... | |||
T76171 | L-Amino acid oxidase | ||
L-Amino acid oxidase, a homodimeric protein that contains flavin adenine dinucleotide, catalyzes the stereospecific oxidative deamination of L-amino acids to α-keto acids and ammonia [1]. | |||
T60806 | Monoamine Oxidase B inhibitor 2 | ||
Monoamine Oxidase B inhibitor 2 is a potent, reversible, orally active and selective inhibitor of monoamine oxidase B (MAO-B) (IC50 = 1.33 nM) which can across the blood-brain barrier (BBB). Monoamine Oxidase B inhibitor... | |||
T61463 | Monoamine oxidase/Aromatase-IN-1 | ||
Monoamine oxidase/Aromatase-IN-1 (compound 2q) is a potent dual inhibitor of monoamine oxidase (MAO) and aromatase, with IC50 values of 39 nM and 31 nM for MAO-B and aromatase, respectively. It holds significant potentia... | |||
T60656 | Monoamine Oxidase B inhibitor 1 | ||
Monoamine Oxidase B inhibitor 1 is a potent, reversible, orally active and selective monoamine oxidase B (MAO-B) inhibitor (IC50 = 0.02 nM) that can across the blood-brain barrier (BBB). Monoamine Oxidase B inhibitor 1 s... | |||
T72299 | Mtb-cyt-bd oxidase-IN-3 | ||
Mtb-cyt-bd oxidase-IN-3, an inhibitor of Mycobacterium tuberculosis cytochrome bd oxidase (Mtb cyt-bd oxidase), exhibits an IC50 value of 0.36 μM and demonstrates an ability to inhibit the growth of Mycobacterium tubercu... | |||
T72305 | Mtb-cyt-bd oxidase-IN-7 | ||
Mtb-cyt-bd oxidase-IN-7, a cytochrome bd terminal oxidase (Cyt-bd) inhibitor, exhibits anti-tuberculosis activities with a dissociation constant (Kd) of 4.17 μM. | |||
T72297 | Mtb-cyt-bd oxidase-IN-1 | ||
Mtb-cyt-bd oxidase-IN-1 is a potent inhibitor of Mycobacterium tuberculosis cytochrome bd oxidase, possessing an inhibition constant (IC50) of 0.13 μM, making it valuable for tuberculosis research. | |||
T72300 | Mtb-cyt-bd oxidase-IN-4 | ||
Mtb-cyt-bd oxidase-IN-4, an inhibitor of Mycobacterium tuberculosis cytochrome bd oxidase (Mtb cyt-bd oxidase), demonstrates potent activity with an IC50 value of 0.25 μM and inhibits the growth of Mycobacterium tubercul... | |||
T72302 | Mtb-cyt-bd oxidase-IN-6 | ||
Mtb-cyt-bd oxidase-IN-6, a potent inhibitor of Mycobacterium tuberculosis (Mtb) cytochrome bd (cyt-bd) oxidase (MtbCyt-bd Oxidase), exhibits an inhibitory concentration (IC50) of 0.35 μM and effectively suppresses Mtb gr... | |||
T4559 | Isocarboxazid | Monoamine Oxidase | |
Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor.[2] It is used in the treatment of major depression, dysthymic disorder, atypical disor... | |||
T22605 | Bifemelane hydrochloride | MAO , Monoamine Oxidase | |
Bifemelane hydrochloride is a MAO inhibitor | |||
T39986 | LOX-IN-3 dihydrochloride | Lipoxygenase | |
LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX). LOX-IN-3 dihydrochloride inhibited bovine LOX (IC50<10 μM) and human LOXL2 (IC50<1 μM)activities. | |||
T8849 | PF-9601N | MAO | |
PF-9601N showed high potency and selectivity as a MAO-BI (monoamine oxidase type B inhibitor) and also demonstrated remarkable neuroprotective properties in several in vivo and cellular models of PD. | |||
T39280 | Nitrofen | Others | |
Nitrofen is a selective contact herbicide. Nitrofen is a protoporphyrinogen oxidase and retinal dehydrogenase inhibitor. | |||
T0235 | Modaline sulfate | MAO , Monoamine Oxidase | |
Modaline was a 2-methyl-3-piperidinopyrazine derivative found to inhibit monoamine oxidase (MAO) and showed a curative effect for the anti-depressant. Similar to other MAO inhibitors, it enhanced convulsions induced by t... | |||
T0084 | Moclobemide | Ro111163 | MAO , Monoamine Oxidase |
Moclobemide (Ro111163) is a reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties. | |||
T12585 | PXS-5153A | Others , Monoamine Oxidase | |
PXS-5153A is an effective, selective, and fast-acting inhibitor of lysyl oxidase like 2/3 enzymes with enzymatic activity almost entirely blocked within 15 minutes. PXS-5153A could reduce crosslinks and ameliorates fibro... | |||
T12584 | PXS-5120A | Others , Monoamine Oxidase | |
PXS-5120A is an irreversible fluoroallylamine Lysyl Oxidase-like 2/3 (LOXL2/3) inhibitor with anti-fibrotic activity. | |||
T1993 | J-147 | J147 | Epigenetic Reader Domain , Dopamine Receptor , Monoamine Oxidase |
J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate... | |||
T3596 | TB5 | MAO , Monoamine Oxidase | |
TB5 is a potent, selective and reversible inhibitor of hMAO-B. | |||
T8337 | Nequinate | Xanthine Oxidase , Parasite | |
Nequinate is an anticoccidial agent, preventing coccidiosis . | |||
T7626 | Budipine | Others | |
Budipine is a low affinity, N-methyl-D-aspartate receptor antagonist,is an antiparkinsonian agent. | |||
T4359 | VAS2870 | NADPH | |
VAS2870 is an inhibitor of NADPH oxidase (NOX). | |||
T8107 | GLX351322 | NADPH-oxidase , NADPH | |
GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T75505 | Xanthine oxidase-IN-9 | ||
Xanthine Oxidase-IN-9 (also known as Icarisids E or Compound 2) effectively inhibits xanthine oxidase (XOD) with an IC50 value of 31.81 μM [1]. | |||
T75504 | Xanthine oxidase-IN-8 | ||
Xanthine oxidase-IN-8 (Icarisids J) (Compound 7) serves as an inhibitor of xanthine oxidase, exhibiting an inhibitory concentration (IC50) value of 29.71 μM [1]. | |||
T16685 | Purpurogallin | Xanthine Oxidase | |
Purpurogallin is a naturally phenol extracted from the plants of Quercus spp. It has effective xanthine oxidase inhibitory activity (IC50: 0.2 µM). Purpurogallin also has antioxidant and anti-inflammatory effects. | |||
TN1120 | Osthenol | MAO , Monoamine Oxidase | |
Osthenol is a natural product, and is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM).It shows antitumor-promoting activity, it also has antifungal and antibacterial activ... | |||
T2900 | Paeonol | Peonol | MAO , Autophagy , Monoamine Oxidase |
Paeonol (Peonol) is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively. | |||
T1694 | Oxypurinol | Oxipurinol | ROS , Xanthine Oxidase , Endogenous Metabolite |
Oxypurinol is a xanthine oxidase inhibitor. Oxipurinol is potentially used for the treatment of congestive heart failure. | |||
T3158 | Harmane | Loturine,Harman,Aribine | Adrenergic Receptor , Monoamine Oxidase , Imidazoline Receptor |
Harmane (Loturine) is a bio-active β-Carboline and monoamine oxidase inhibitor found in coffee and tobacco smoke. | |||
TN2004 | Obtusin | MAO , Monoamine Oxidase | |
Obtusin is a natural product. | |||
T3152 | Harmol | Methylpyridoindolol | Others |
Harmol (Methylpyridoindolol) is a β-carboline isolated from nature. | |||
T13475 | β-Aminopropionitrile | 3-Aminopropionitrile,BAPN | Others , Endogenous Metabolite |
β-Aminopropionitrile (3-Aminopropionitrile) is a selective inhibitor of lysyl oxidase. | |||
T4024 | Norharmane | 2-Azacarbazole,2,9-Diazafluorene,β-Carboline | DNA , Endogenous Metabolite , Monoamine Oxidase |
Norharmane (β-Carboline) is a natural β-carboline first isolated from plants of the Zygophyllaceae family. | |||
T2858 | Baicalein | 5,6,7-Trihydroxyflavone | Ferroptosis , Influenza Virus , ROS , Xanthine Oxidase |
Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor. | |||
T6862 | Isatin | Pseudoisatin,Indoline-2,3-dione,2,3-Indolinedione | Apoptosis , MAO , Monoamine Oxidase |
Isatin (2,3-Indolinedione) is an endogenous MAO inhibitor. | |||
T10933 | D-Cysteine | Endogenous Metabolite , Antibacterial | |
D-Cysteine is the D-isomer of cysteine and a powerful inhibitor of the growth of E. coli. D-cysteine is mediated by D-amino acid oxidase to produce H2S, and is a neuroprotective agent against cerebellar ataxia. D-cystein... | |||
TMA0958 | Forsythoside F | Arenarioside | Xanthine Oxidase |
Forsythoside F (Arenarioside) is a natural product, and GI50 values of 10-16 microM against B16F10 cell. | |||
T5S0734 | Desmethoxyyangonin | Desmethoxy yangonin,Demethoxyyangonin,5,6-Dehydrokavain | Others , Monoamine Oxidase |
1. Desmethoxyyangonin (5,6-Dehydrokavain) protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. 2. The induction of CYP3A23 by dihydr... | |||
T2765 | Rosmarinic acid | Labiatenic acid,Rosemary acid | Apoptosis , IκB/IKK , MAO , Endogenous Metabolite , Transferase , Monoamine Oxidase |
Rosmarinic acid (Labiatenic acid) is widely found in plants and has antioxidant, anti-inflammatory, and antibacterial activities. It inhibits MAO-A, MAO-B, and COMT with IC50 of 50.1, 184.6, and 26.7 μM respectively. | |||
T3885 | ROSIRIDIN | 6'-O-Deacetylrosiridoside C,(-)-Rosiridin | Others , Monoamine Oxidase |
Rosiridin (6'-O-Deacetylrosiridoside C) has cardioprotective activity. | |||
T2971 | Phytic acid | Inositol hexaphosphate,inositol hexakisphosphate,inositol polyphosphate,myo-Inositol, hexakis(dihydrogen phosphate),Fytic Acid | Xanthine Oxidase , Endogenous Metabolite |
Phytic acid (Fytic Acid) is a complexing agent for removal of traces of heavy metal ions. It acts also as a hypocalcemic agent. | |||
T12564 | Prudomestin | 3,5,7-Trihydroxy-4',8-dimethoxyflavone | Xanthine Oxidase |
Prudomestin (3,5,7-Trihydroxy-4',8-dimethoxyflavone) is a natural product isolated from the heartwood of Prunus domestica, with xanthine oxidase (XO) inhibitory activity with IC50 of 6 µM. | |||
T16527 | Phytic acid dodecasodium salt hydrate | myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate,Inositol hexaphosphate dodecasodium salt hydrate | Others , Xanthine Oxidase , Endogenous Metabolite |
Phytic acid dodecasodium salt hydrate (myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate) is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium salt hydrate inhibits th... | |||
T6S0923 | Hypericin | Hypericine,Cyclosan | Apoptosis , Antiviral , Influenza Virus , Tyrosine Kinases , Antibacterial , PKC |
1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL... | |||
T6391 | Apocynin | Acetovanillone,Acetoguaiacone,NSC 2146 | Apoptosis , NADPH , Autophagy |
Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM). | |||
T21213 | Benzylurea | AI3-61350,Benzylcarbamide,Phenylmethylurea,1-Benzylurea,N-Benzylurea | Others |
Benzylurea (AI3-61350) competitively inhibits dehydrogenase/cytokinin oxidase. | |||
T1363 | N-Demethylricinine | 4-Methoxy-2-oxo-1,2-dihydro-pyridine-3-carbonitrile | ROS |
N-Demethylricinine (4-Methoxy-2-oxo-1,2-dihydro-pyridine-3-carbonitrile) was reported as xanthine oxidase inhibitor. | |||
Fr12415 | Ethyl 4-hydroxyphenylacetate | Others | |
Ethyl 4-hydroxyphenylacetate is a selective inhibitor of monoamine oxidase A. | |||
T19302 | D(-)-2-Aminobutyric acid | Endogenous Metabolite | |
D(-)-2-Aminobutyric acid is the substrate of D-amino acid oxidase. | |||
TN7211 | Tetrahydroharmine | Leptaflorine | MAO |
Tetrahydroharmine (Leptaflorine) is a natural product found in the stems and large branches of Banisteriopsis caapi cultivar Da Vine. Tetrahydroharmine is a Monoamine oxidase A inhibitor. | |||
TQ0188 | Miquelianin | Quercetin 3-glucuronide,Quercetin 3-O-glucuronide | stilbene oxidase , Endogenous Metabolite |
Miquelianin (Quercetin 3-glucuronide) is a potent stilbene oxidase inhibitor, it has antioxidant, anti-atherogenic, and anti-inflammatory activities. | |||
TN1002 | Blumeatin | ROS | |
Blumeatin has antioxidant properties, free radical scavenging activity,and has xanthine oxidase (XO) inhibitory activity. | |||
T3750 | 4-Hydroxyacetophenone | 4-Acetylphenol,Piceol,p-Acetylphenol,4'-Hydroxyacetophenone | HBV , Xanthine Oxidase |
4-Hydroxyacetophenone (4-Acetylphenol) is a potent xanthine oxidase inhibitor. | |||
TN1705 | Glycyrrhisoflavone | MAO , Tyrosinase , NO Synthase , Immunology/Inflammation related | |
Glycyrrhisoflavone is a tyrosinase inhibitor with anti-inflammatory effects. Glycyrrhisoflavone inhibits α-glucosidase and monoamine oxidase. | |||
T5300 | Ammonium formate | Formic acid ammonium salt | Others |
Ammonium formate (Formic acid ammonium salt) is the simplest carboxylic acid. Formate is an intermediate in normal metabolism. It is responsible for both metabolic acidosis and disrupting mitochondrial electron transport... | |||
T4716 | Pyrrole-2-carboxylic acid | 2-Pyrrolecarboxylic acid,Minaline | Endogenous Metabolite |
Pyrrole-2-carboxylic acid (Minaline) was first identified as a degradation product of sialic acids, then as a derivative of the oxidation of the D-hydroxyproline isomers by mammalian D-amino acid oxidase. The latter rela... | |||
TN1962 | Myricetin 3-O-galactoside | Myricetin 3-O-beta-D-galactopyranoside | NOS , Xanthine Oxidase |
Myricetin 3-O-galactoside (Myricetin 3-O-beta-D-galactopyranoside) can inhibit xanthine oxidase (xanthine oxidase; XO) activity, lipid peroxidation and scavenging free radicals. Myricetin 3-O-galactoside has many effects... | |||
TN2126 | Quercetin-3-O-glucose-6''-acetate | 6"-O-Acetylisoquercitrin | NADPH-oxidase , ROS , NADPH |
Quercetin-3-O-glucose-6''-acetate (6"-O-Acetylisoquercitrin) is an inhibitor of NADPH oxidase. Quercetin-3-O-glucose-6''-acetate has antioxidant activities. | |||
T3740 | Isovanillin | 3-Hydroxy-p-anisaldehyde,3-Hydroxy-4-methoxybenzaldehyde,5-Formylguaiacol | Others |
Isovanillin (5-Formylguaiacol) is a reversible inhibitor of aldehyde oxidase. It is largely used as pharmaceutical intermediates and also applied in food and beverage industry, synthetic fragrances, chemical. | |||
T21164 | Sulfentrazone | FP-846 | Others |
Sulfentrazone (FP-846) is purified form of sulfentrazone which acts as a protoporphyrinogen oxidase inhibitor.It is a phenyl triazolinone herbicide | |||
T13354 | Xanthoangelol | Apoptosis , Monoamine Transporter , Antibacterial , AMPK | |
Xanthoangelol, which can be extracted from Angelica keiskei, inhibits obesity-induced inflammatory responses.Xanthoangelol has antimicrobial activity, inhibits monoamine oxidase, and induces apoptosis in neuroblastoma an... | |||
T4455 | DL-3-Phenyllactic acid | 3-Phenyllactic acid,2-Hydroxy-3-phenylpropanoic acid | Others , Endogenous Metabolite , Antibacterial |
3-Phenyllactic acid (PhLA) is a broad spectrum antimicrobial compound active against bacteria and fungi, DL-3-Phenyllactic acid (3-Phenyllactic acid) is a reagent involved in biological studies of nantioselectivity of li... | |||
T0617 | Nicotinamide N-oxide | Nicotinamide-N-oxide,Nicotinamide 1-oxide,1-oxynicotinamide | c-Myc , Endogenous Metabolite , CXCR , Drug Metabolite |
Nicotinamide N-oxide (Nicotinamide 1-oxide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD+) in animals. The enzyme that catalyzes the reduction of n... | |||
T0626 | Uric Acid | 2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate | Reactive Oxygen Species , Endogenous Metabolite , Phosphorylase |
Uric Acid (Lithic acid) is an oxidation product of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE ... | |||
T10938 | D-Kynurenine | (R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103 | GPR , AhR , Endogenous Metabolite |
D-Kynurenine (ZINC901103) is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and promotes the conversion of the epithelium to mesenchyme. D-Kynurenine serves as a substrate in the fluor... | |||
T3095 | Tyramine | 4-hydroxyphenethylamine,para-tyramine,p-Tyramine,mydrial,Tocosine,Uteramine | MAO , Endogenous Metabolite |
Tyramine (Uteramine) is an indirect sympathomimetic that occurs naturally in cheese and other foods. Tyramine does not directly activate adrenergic receptors, but it can serve as a substrate for adrenergic uptake systems... | |||
TN1470 | Cassiaside B2 | Phosphatase , MAO , 5-HT Receptor | |
Cassiaside B2 is an inhibitor of protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A).Cassiaside B2 is an agonist of the 5-HT2C receptor with anti-allergic activity.Cassiaside B2 is one of the a... | |||
T3933 | Jatrorrhizine | Yatrorizine,neprotin | MAO , 5-HT Receptor , Antibacterial , AChE |
Jatrorrhizine (neprotin) is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal activity. It binds and noncompetitively inhibits mo... | |||
T5S0281 | Tubuloside A | NOS | |
Tubuloside A ( 8.6 microM) can inhibit D-galactosamine-induced death of hepatocytes. Tubuloside A has NO radical-scavenging activity, which possibly contributes to its anti-inflammatory effects.Tubuloside A shows stronge... | |||
T4719 | 1,4-D-Gulonolactone | D-Gulonic acid γ-lactone | Others , Endogenous Metabolite |
1,4-D-Gulonolactone (D-Gulonic acid γ-lactone) (also known as reduced ascorbic acid, RAA) is the substrate of the enzyme L-gulono-1,4-lactone oxidoreductase (EC 1.1.3.8), which catalyzes the last step of the biosynthesis... | |||
T0665 | Xanthine | 2,6-Dihydroxypurine,Isoxanthine | Endogenous Metabolite , Adenosine Receptor |
Xanthine (Isoxanthine) is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme. Xanthine is found in most body tissues and fluids in... | |||
T5S2343 | Acetylshikonin | Acetyl shikonin | Others , P450 , AChE |
1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC5 of over 2 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and ang... | |||
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Cat No. | Product Name | Species | Expression System |
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TMPY-00203 | LOXL2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 ... | |||
TMPY-02481 | ACOX1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Peroxisomal acyl-coenzyme A oxidase 1(ACOX1 or AOX) is the first enzyme of the fatty acid beta-oxidation pathway and belongs to the Acyl-CoA oxidase family. Human liver peroxisomes contain two acyl-CoA oxidases, namely, ... | |||
TMPY-01770 | HAO1 Protein, Human, Recombinant (His) | Human | E. coli |
Hydroxyacid oxidase 1, also known as Glycolate oxidase, HAO1, and GOX1, is a member of the FMN-dependent alpha-hydroxy acid dehydrogenase family. HAO1 / GOX1 has 2-hydroxyacid oxidase activity. It is most active on the 2... | |||
TMPH-00913 | AOX1 Protein, Human, Recombinant (His) | Human | E. coli |
AOX1 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-02825 | ACOX1 Protein, Mouse, Recombinant (Myc) | Mouse | E. coli |
Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. First enzyme of the fatty acid beta-oxidation pathway.; Shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing ch... | |||
TMPJ-00380 | AOC3 Protein, Human, Recombinant (His) | Human | Human Cells |
Vascular adhesion protein-1(VAP-1) is a copper amine oxidase with a topaquinone cofactor.VAP-1 is a type II integral membrane protein, but a soluble form of the enzyme is present in human serum, and its level increases i... | |||
TMPJ-00379 | AOC3 Protein, Human, Recombinant (hFc) | Human | Human Cells |
Membrane primary amine oxidase(AOC3), also known as vascular adhesion protein (VAP-1) and HPAO, this protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family. VAP-1 is a type 1 membrane-bound glycop... | |||
TMPH-03639 | COX7A1 Protein, Trachypithecus cristatu, Recombinant (hFc) | Trachypithecus cristatus | HEK293 |
COX7A1 Protein, Trachypithecus cristatu, Recombinant (hFc) is expressed in HEK293. | |||
TMPH-00757 | Reticuline oxidase Protein, Eschscholzia californica, Recombinant (His) | Eschscholzia californica | E. coli |
Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbo... | |||
TMPH-01180 | COX5A Protein, Human, Recombinant (GST) | Human | E. coli |
COX5A Protein, Human, Recombinant (GST) is expressed in E. coli. | |||
TMPH-00127 | Glucose oxidase Protein, Aspergillus niger, Recombinant (His) | Aspergillus niger | Baculovirus |
Glucose oxidase Protein, Aspergillus niger, Recombinant (His) is expressed in Baculovirus. | |||
TMPY-03511 | COX5B Protein, Human, Recombinant (His) | Human | E. coli |
Cytochrome C oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contribut... | |||
TMPJ-00853 | DAO Protein, Human, Recombinant (His) | Human | E. coli |
D-Amino-Acid Oxidase (DAO) belongs to the DAMOX/DASOX family. DAO is a peroxisomal enzyme which founctions as a homodimer to oxidizes D-amino acids to the corresponding imino acids, producing ammonia and hydrogen peroxid... | |||
TMPH-02617 | COX5A Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase... | |||
TMPH-00103 | Probable sarcosine oxidase Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | E. coli |
Probable sarcosine oxidase Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli. | |||
TMPH-03605 | CHOD Protein, Streptomyces sp., Recombinant (GST) | Streptomyces sp. | E. coli |
CHOD Protein, Streptomyces sp., Recombinant (GST) is expressed in E. coli. | |||
TMPH-00166 | Glycine oxidase Protein, Bacillus subtilis, Recombinant (His & SUMO) | Bacillus subtilis | E. coli |
Glycine oxidase Protein, Bacillus subtilis, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-00035 | Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His) | Agaricus bisporus | Baculovirus |
Copper-containing oxidase that catalyzes both the o-hydroxylation of monophenols and the subsequent oxidation of the resulting o-diphenols into reactive o-quinones, which evolve spontaneously to produce intermediates, wh... | |||
TMPH-00128 | Glucose oxidase Protein, Aspergillus niger, Recombinant (E. coli, His) | Aspergillus niger | E. coli |
Glucose oxidase Protein, Aspergillus niger, Recombinant (E. coli, His) is expressed in E. coli. | |||
TMPH-00824 | Oxalate oxidase 1 Protein, Hordeum vulgare, Recombinant (His & Myc) | Hordeum vulgare | E. coli |
Releases hydrogen peroxide in the apoplast which may be important for cross-linking reactions in the cell wall biochemistry. May play an important role in several aspects of plant growth and defense mechanisms. | |||
TMPH-03485 | L-saccharopine oxidase Protein, S. pombe, Recombinant (His & Myc) | Fission yeast | E. coli |
L-saccharopine oxidase Protein, S. pombe, Recombinant (His & Myc) is expressed in E. coli with N-terminal 10xHis tag and C-terminal Myc tag. The predicted molecular weight is 52.2 kDa. Accession number: Q9UTM9 | |||
TMPH-00036 | Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His & Myc) | Agaricus bisporus | E. coli |
Copper-containing oxidase that catalyzes both the o-hydroxylation of monophenols and the subsequent oxidation of the resulting o-diphenols into reactive o-quinones, which evolve spontaneously to produce intermediates, wh... | |||
TMPH-01179 | COX4I1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
COX4I1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-01225 | DHODH Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | |||
TMPH-00453 | L-ascorbate oxidase Protein, Cucurbita maxima, Recombinant (His & SUMO) | Cucurbita maxima | E. coli |
L-ascorbate oxidase Protein, Cucurbita maxima, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-02627 | DHODH Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | |||
TMPY-00140 | ABP1/AOC1 Protein, Human, Recombinant (His) | Human | HEK293 |
Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putres... | |||
TMPH-03278 | DHODH Protein, Rat, Recombinant (His) | Rat | E. coli |
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | |||
TMPH-02621 | DAO Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during agi... | |||
TMPH-02850 | DHODH Protein, Mouse, Recombinant (His) | Mouse | in vitro E. coli expression system |
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | |||
TMPH-03276 | DAO Protein, Rat, Recombinant (His & Myc) | Rat | E. coli |
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during agi... | |||
TMPJ-00938 | 4HPPD Protein, Human, Recombinant (His) | Human | E. coli |
4-Hydroxyphenylpyruvate Dioxygenase (4HPPD) belongs to the 4HPPD family. 4HPPD is a key enzyme in the degradation of tyrosine, which catalyzes the second reaction in the catabolism of tyrosine the conversation of 4-hydro... | |||
TMPJ-01020 | GFER Protein, Human, Recombinant (His) | Human | E. coli |
GFER is a hepatotrophic growth factor and flavin-linked sulfhydryl oxidase which belongs to the Erv1/ALR family of proteins. GFER is widely expressed in various human tissues. They are two isoforms of this protein. Isofo... | |||
TMPJ-00848 | NCF1 Protein, Human, Recombinant (His) | Human | E. coli |
Neutrophil cytosol factor 1( NCF1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is characterized as a multicomponent enzyme which is activated to produce superoxide anion. NCF2, NCF1, and a mem... | |||
TMPH-01277 | ENOX2 Protein, Human, Recombinant | Human | E. coli |
May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a ... | |||
TMPH-01278 | ENOX2 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a ... | |||
TMPH-03751 | CYBB Protein, Human, Recombinant (His) | Human | E. coli |
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membr... | |||
TMPY-02779 | Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His) | Human | Baculovirus-Insect Cells |
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoant... | |||
TMPY-05252 | Myeloperoxidase/MPO Protein, Human, Recombinant (His) | Human | HEK293 |
MPO (myeloperoxidase) is a peroxidase enzyme secreted by activated leukocytes that plays a pathogenic role in cardiovascular disease, mainly by initiating endothelial dysfunction. Myeloperoxidase (MPO) is an important en... | |||
TMPH-02407 | Peroxidase Protein, Lentinula edodes, Recombinant (His & Myc) | Lentinula edodes | E. coli |
Peroxidase Protein, Lentinula edodes, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPK-00874 | Thyroid Peroxidase Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormon... | |||
TMPH-01600 | Lactoperoxidase/LPO Protein, Human, Recombinant (His & Myc) | Human | HEK293 |
Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN). May contribute to airway host defense against infection. | |||
TMPY-03619 | P67phox Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
NCF2 (Neutrophil Cytosolic Factor 2, also known as NCF-2 and p67phox) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. This gene encodes neutrophil cytosolic factor 2, the 67-kilodalto... | |||
TMPY-03660 | P67phox Protein, Human, Recombinant | Human | Baculovirus-Insect Cells |
NCF2 (Neutrophil Cytosolic Factor 2, also known as NCF-2 and p67phox) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. This gene encodes neutrophil cytosolic factor 2, the 67-kilodalto... | |||
TMPH-01276 | ENOX1 Protein, Human, Recombinant (His) | Human | E. coli |
Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol intercha... | |||
TMPY-04475 | RFK Protein, Human, Recombinant (His) | Human | E. coli |
Flavokinase is a member of the transferases family, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. Flavokinase is an essential enzyme that catalyzes ... | |||
TMPH-02474 | HAOX1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate. | |||
TMPH-01630 | LOXL3 Protein, Human, Recombinant (GST & His) | Human | E. coli |
Protein-lysine 6-oxidase that mediates the oxidation of peptidyl lysine residues to allysine in target proteins. Catalyzes the post-translational oxidative deamination of peptidyl lysine residues in precursors of elastin... | |||
TMPH-00866 | ADAMTS14 Protein, Human, Recombinant (His) | Human | E. coli |
Has aminoprocollagen type I processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity. Cleaves lysyl oxidase LOX at ... | |||
TMPH-03711 | PPAR gamma Protein, Xenopus laevis, Recombinant (His) | Xenopus laevis | E. coli |
Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcript... | |||
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Cat No. | Product Name | ||
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L9830 | Anti-Parkinson's Disease Compound Library | 908 compounds | |
A unique collection of 908 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS. |