Glucose-6-phosphate dehydrogenase, the crucial rate-limiting enzyme in the pentose phosphate pathway, plays a vital role in generating NADPH. This compound is indispensable for numerous critical cellular functions such as antioxidant pathways, nitric oxide synthase, NADPH oxidase, and the cytochrome p450 system, among others. Its significance extends to research applications in diabetes, aldosterone-induced endothelial dysfunction, and cancer [1].