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7-Hydroxy-3,4-dihydro-2(1H)-quinolinone

7-Hydroxy-3,4-dihydro-2(1H)-quinolinone
7-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a weak MAO-A inhibitor(with an IC50 of 183 μM) .
Catalog No. T5887Cas No. 22246-18-0
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7-Hydroxy-3,4-dihydro-2(1H)-quinolinone

Catalog No. T5887Alias 3,4-Dihydro-7-hydroxy-2(1H)-quinolinoneCas No. 22246-18-0

7-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a weak MAO-A inhibitor(with an IC50 of 183 μM) .
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Pack SizePriceAvailabilityQuantity
500 mg$29In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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Product Introduction

Bioactivity
Description
7-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a weak MAO-A inhibitor(with an IC50 of 183 μM) .
Targets&IC50
MAO-A:183 μM
Alias3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
Chemical Properties
Molecular Weight163.17
FormulaC9H9NO2
Cas No.22246-18-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 32 mg/mL (196.11 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM6.1286 mL30.6429 mL61.2858 mL306.4289 mL
5 mM1.2257 mL6.1286 mL12.2572 mL61.2858 mL
10 mM0.6129 mL3.0643 mL6.1286 mL30.6429 mL
20 mM0.3064 mL1.5321 mL3.0643 mL15.3214 mL
50 mM0.1226 mL0.6129 mL1.2257 mL6.1286 mL
100 mM0.0613 mL0.3064 mL0.6129 mL3.0643 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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