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Toloxatone
Catalog No. T5323Cas No. 29218-27-7
Alias MD 69276
Toloxatone (MD 69276) is a reversible inhibitor of monoamine oxidase A (MAOA).
Toloxatone
Catalog No. T5323Alias MD 69276Cas No. 29218-27-7
Toloxatone (MD 69276) is a reversible inhibitor of monoamine oxidase A (MAOA).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $52 | In Stock | |
| 10 mg | $89 | In Stock | |
| 25 mg | $189 | In Stock | |
| 50 mg | $327 | In Stock | |
| 100 mg | $559 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $57 | In Stock |
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Purity:99.86%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Toloxatone (MD 69276) is a reversible inhibitor of monoamine oxidase A (MAOA). |
| In vivo | The maximum increase in systolic blood pressure produced by four single oral doses of tyramine administered during a meal and ranging from 100 mg to 800 mg was compared during repeated (3 to 5 days) administration of placebo, 200 mg toloxatone three times a day and 400 mg toloxatone three times a day in a single-blind, three-period crossover study. Toloxatone by itself had no significant influence on blood pressure. During administration of toloxatone, no significant increase in tyramine-induced increase in systolic blood pressure was observed for tyramine doses of 200 mg or less that are consistently higher than those associated with normal food intake [2]. |
| Alias | MD 69276 |
| Molecular Weight | 207.23 |
| Formula | C11H13NO3 |
| Cas No. | 29218-27-7 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (241.3 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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