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D-Kynurenine
🥰Excellent
Catalog No. T10938Cas No. 13441-51-5
Alias ZINC901103, (R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
D-Kynurenine (ZINC901103) is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and promotes the conversion of the epithelium to mesenchyme. D-Kynurenine serves as a substrate in the fluorescence analysis of D-amino acid oxidase.
D-Kynurenine
🥰Excellent
Purity: 97.08%
Catalog No. T10938Alias ZINC901103, (R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acidCas No. 13441-51-5
D-Kynurenine (ZINC901103) is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and promotes the conversion of the epithelium to mesenchyme. D-Kynurenine serves as a substrate in the fluorescence analysis of D-amino acid oxidase.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $48 | In Stock | |
| 50 mg | $82 | In Stock | |
| 100 mg | $132 | In Stock | |
| 200 mg | $195 | In Stock |
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Purity:97.08%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | D-Kynurenine (ZINC901103) is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and promotes the conversion of the epithelium to mesenchyme. D-Kynurenine serves as a substrate in the fluorescence analysis of D-amino acid oxidase. |
| In vitro | D-Kynurenine (10-100 µM) induces DER-enhancement and positively regulates the transfer of 95D cells, which is attenuated after siRNAAhr treatment in VIM and E-cadherin. D-Kynurenine (10 and 40 µM) significantly increases VIM expression and induces CYP1A1 upregulation. D-Kynurenine (10 µM) significantly attenuates the level of E-cadherin[4]. |
| Alias | ZINC901103, (R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid |
| Molecular Weight | 208.21 |
| Formula | C10H12N2O3 |
| Cas No. | 13441-51-5 |
| Smiles | N[C@H](CC(=O)c1ccccc1N)C(O)=O |
| Relative Density. | 1.343 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | H2O: 5 mg/mL (24.01 mM), Sonication and heating to 60℃ are recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
H2O
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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