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ND-011992

ND-011992
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Purity:99.7%
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ND-011992

Catalog No. T77615Cas No. 2446880-46-0
ND-011992 is a reversible and selective quinazoline inhibitor targeting quinone reductases and quinol oxidases.ND-011992 inhibits E. coli BL21*Δcyo respiratory complex I. ND-011992 inhibits bo3 oxidase, bd-I oxidases and bd-II oxidases, ND-011992 inhibits E. coli BL21*Δcyo respiratory complex I, bo3 oxidase, bd-I oxidases, and bd-II oxidases with IC50s of 0.12, 2.47, 0.63, and 1.3 μM, respectively.ND-011992 can be used in the study of tuberculosis.
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Pack SizePriceAvailabilityQuantity
1 mg$93In Stock
5 mg$228In Stock
10 mg$328In Stock
25 mg$562In Stock
50 mg$793In Stock
100 mg$1,130In Stock
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Product Introduction

Bioactivity
Description
ND-011992 is a reversible and selective quinazoline inhibitor targeting quinone reductases and quinol oxidases.ND-011992 inhibits E. coli BL21*Δcyo respiratory complex I. ND-011992 inhibits bo3 oxidase, bd-I oxidases and bd-II oxidases, ND-011992 inhibits E. coli BL21*Δcyo respiratory complex I, bo3 oxidase, bd-I oxidases, and bd-II oxidases with IC50s of 0.12, 2.47, 0.63, and 1.3 μM, respectively.ND-011992 can be used in the study of tuberculosis.
In vitro
ND-011992 inhibits bovine heart mitochondrial membrane NADH oxidase activity with an IC50 of 3.27 µM.[1]
AliasND011992
Chemical Properties
Molecular Weight381.35
FormulaC21H14F3N3O
Cas No.2446880-46-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (157.34 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6223 mL13.1113 mL26.2226 mL131.1132 mL
5 mM0.5245 mL2.6223 mL5.2445 mL26.2226 mL
10 mM0.2622 mL1.3111 mL2.6223 mL13.1113 mL
20 mM0.1311 mL0.6556 mL1.3111 mL6.5557 mL
50 mM0.0524 mL0.2622 mL0.5245 mL2.6223 mL
100 mM0.0262 mL0.1311 mL0.2622 mL1.3111 mL

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