Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Plx-4032 (Vemurafenib) is a small-molecule B-Raf inhibitor for the potential treatment of malignant melanoma.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 50.00 | |
50 mg | In stock | $ 72.00 | |
100 mg | In stock | $ 100.00 | |
200 mg | In stock | $ 180.00 | |
500 mg | In stock | $ 306.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Plx-4032 (Vemurafenib) is a small-molecule B-Raf inhibitor for the potential treatment of malignant melanoma. |
In vivo | PLX-4032 and its related analogs are highly potent inhibitors of B-Raf activity, with 3-fold selectivity for the V600E mutation over the wild-type kinase.?In preclinical models, PLX-4032 and its analogs inhibited the growth of BRAFV600E-positive melanoma cell lines both in vitro and in vivo[1]. |
Synonyms | Vemurafenib |
Molecular Weight | 489.92 |
Formula | C23H18ClF2N3O3S |
CAS No. | 1029872-54-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (61.23 mM)
You can also refer to dose conversion for different animals. More
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Plx-4032 1029872-54-5 MAPK Raf Vemurafenib Plx 4032 Plx4032 18504-65-1 inhibitor inhibit