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S1PR1 modulator 1

Catalog No. T12821   CAS 2328109-05-1

S1PR1 modulator 1 is a selective inhibitor of S1PR1 with a pIC50 of 7.6.

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S1PR1 modulator 1 Chemical Structure
S1PR1 modulator 1, CAS 2328109-05-1
Pack Size Availability Price/USD Quantity
1 mg In stock $ 59.00
5 mg In stock $ 122.00
10 mg In stock $ 173.00
25 mg In stock $ 285.00
50 mg In stock $ 422.00
100 mg In stock $ 626.00
1 mL * 10 mM (in DMSO) In stock $ 141.00
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Purity: 99.44%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description S1PR1 modulator 1 is a selective inhibitor of S1PR1 with a pIC50 of 7.6.
Targets&IC50 S1PR3:6(pIC50), S1PR1:7.6(pIC50)
In vitro S1PR1 modulator 1 shows >40- and >80-fold selectivity, over the other S1PR isoforms S1PR3 (pIC50, 6), S1PR2 and S1PR4 (pIC50s, <5)[1].
Molecular Weight 408.51
Formula C23H24N2O3S
CAS No. 2328109-05-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 6.11 mg/mL (14.96 mM)

TargetMolReferences and Literature

1. Bell M, et al. Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1). ACS Med Chem Lett. 2019 Feb 14;10(3):341-347.

Related compound libraries

This product is contained In the following compound libraries:
Bioactive Compounds Library Max Inhibitor Library Bioactive Compound Library

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Keywords

S1PR1 modulator 1 2328109-05-1 GPCR/G Protein LPL Receptor S-1PR1 modulator 1 inhibit Lysophospholipid Receptor Inhibitor inhibitor

 

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