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SQ609 is a potential anti-tuberculosis drug selected from a library of dipiperidine derivatives. SQ609 showed significant anti-tuberculous activity in mouse macrophages in vitro[1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $30 | In Stock | |
5 mg | $63 | In Stock | |
10 mg | $91 | In Stock | |
25 mg | $152 | In Stock | |
50 mg | $247 | In Stock | |
100 mg | $396 | In Stock |
Description | SQ609 is a potential anti-tuberculosis drug selected from a library of dipiperidine derivatives. SQ609 showed significant anti-tuberculous activity in mouse macrophages in vitro[1]. |
In vitro | In vitro studies show that SQ609 effectively inhibits over 90% of intracellular bacterial growth in Mtb-infected macrophages at a concentration of 4μg/ml while also exhibiting toxicity to these cells[1]. |
In vivo | SQ609 (10 mg/kg; administered orally by gavage) completely prevents weight loss in the Mtb-infected animals and prolongs the therapeutic effect following drug withdrawal for another 10-15 days[1]. |
Molecular Weight | 346.55 |
Formula | C22H38N2O |
Cas No. | 627052-25-9 |
Smiles | OC1CCN(CC2CCN(CC34CC5CC(CC(C5)C3)C4)CC2)CC1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO: 1 mg/ml, Sonication is recommended. ![]() |
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