store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TTA-Q6 is a selective T-type Ca2+ channel antagonist with potential antitumor and immunomodulatory activity for the treatment of neurological disorders by inhibiting the uptake of extracellular calcium ions by tumor cells and inducing intracellular calcium deficiency and endoplasmic reticulum (ER) stress.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 106.00 | |
50 mg | 6-8 weeks | $ 722.00 | |
100 mg | 6-8 weeks | $ 997.00 |
Description | TTA-Q6 is a selective T-type Ca2+ channel antagonist with potential antitumor and immunomodulatory activity for the treatment of neurological disorders by inhibiting the uptake of extracellular calcium ions by tumor cells and inducing intracellular calcium deficiency and endoplasmic reticulum (ER) stress. |
In vitro | In the acidic tumor microenvironment, TTA-Q6 is released, disrupting cancer cell calcium uptake, inducing endoplasmic reticulum stress, and promoting the translocation of calcium-binding proteins to the cell surface[1]. |
Molecular Weight | 405.8 |
Formula | C20H15ClF3N3O |
CAS No. | 910484-28-5 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (246.43 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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TTA-Q6 910484-28-5 Membrane transporter/Ion channel Metabolism Calcium Channel TTA-Q-6 TTA Q6 TTAQ6 inhibitor inhibit