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Tetrahydroalstonine
Catalog No. TN2267Cas No. 6474-90-4
Tetrahydroalstonine is an indole alkaloid extracted from the fruit of Rhazya stricta and is a selective α2-adrenoceptor antagonist. tetrahydroalstonine has shown antipsychotic activity in Rauwolfia tetraphylla.
Tetrahydroalstonine
Catalog No. TN2267Cas No. 6474-90-4
Tetrahydroalstonine is an indole alkaloid extracted from the fruit of Rhazya stricta and is a selective α2-adrenoceptor antagonist. tetrahydroalstonine has shown antipsychotic activity in Rauwolfia tetraphylla.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $569 | 7-10 days | |
| 1 mL x 10 mM (in DMSO) | $442 | 7-10 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Tetrahydroalstonine is an indole alkaloid extracted from the fruit of Rhazya stricta and is a selective α2-adrenoceptor antagonist. tetrahydroalstonine has shown antipsychotic activity in Rauwolfia tetraphylla. |
| In vivo | The tetrahydroalstonine (0.5 to 2 mg/kg) on alpha 1- and alpha 2-adrenoceptors were assessed by effects on the rise in blood pressure induced by stimulation of the sympathetic outflow from the spinal cord or by injection of noradrenaline in pithed rats. Tetrahydroalstonine antagonized the effects of injected noradrenaline. Tetrahydroalstonine is more selective for alpha 2-adrenoceptors.[2] |
| Molecular Weight | 352.43 |
| Formula | C21H24N2O3 |
| Cas No. | 6474-90-4 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 90.0 mg/mL (255.4 mM ), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
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