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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $33 | In Stock | |
2 mg | $47 | In Stock | |
5 mg | $77 | In Stock | |
10 mg | $113 | In Stock | |
25 mg | $189 | In Stock | |
50 mg | $278 | In Stock | |
100 mg | $436 | In Stock | |
1 mL x 10 mM (in DMSO) | $133 | In Stock |
Description | Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA) is a synthesized E3 ligase ligand-linker conjugate comprising a Thalidomide-based cereblon ligand and a linker. |
In vitro | PROTACs consist of two ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other targeting the protein of interest. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Alias | E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate, Cereblon Ligand-Linker Conjugates 11 TFA, E3 Ligase Ligand-Linker Conjugates 25 TFA |
Molecular Weight | 1087.95 |
Formula | C46H53F6N8O16 |
Cas No. | 1950635-14-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 105.5 mg/mL (193.76 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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