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Thevetiaflavone
Catalog No. T13922Cas No. 29376-68-9
Alias Apigenin-5-methyl ether, 2-Genistein-5-methyl ether
Thevetiaflavone (2-Genistein-5-methyl ether) is a natural flavonoid from Wikstroemia indica that inhibits the leakage of lactate dehydrogenase from the cytoplasm and increases cell viability.
Thevetiaflavone
Catalog No. T13922Alias Apigenin-5-methyl ether, 2-Genistein-5-methyl etherCas No. 29376-68-9
Thevetiaflavone (2-Genistein-5-methyl ether) is a natural flavonoid from Wikstroemia indica that inhibits the leakage of lactate dehydrogenase from the cytoplasm and increases cell viability.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $872 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Thevetiaflavone (2-Genistein-5-methyl ether) is a natural flavonoid from Wikstroemia indica that inhibits the leakage of lactate dehydrogenase from the cytoplasm and increases cell viability. |
| In vitro | Thevetiaflavone reduces ROS overproduction and ameliorates ROS-mediated mitochondrial dysfunction, including collapse of mitochondrial membrane potential and opening of mitochondrial permeability transition pores, thereby reducing intracellular Ca2+ levels. Thevetiaflavone up-regulates the expression of Bcl-2, down-regulates the expression of Bax and caspase-3 and increases the activity of caspase-3 to inhibit the apoptosis of PC12 cells[1]. |
| Alias | Apigenin-5-methyl ether, 2-Genistein-5-methyl ether |
| Molecular Weight | 284.26 |
| Formula | C16H12O5 |
| Cas No. | 29376-68-9 |
Storage & Solubility Information
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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