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JAMM protein inhibitor 2

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Purity:98.82%

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COA HNMR HPLC

JAMM protein inhibitor 2

Catalog No. T9892Cas No. 848249-35-4

JAMM protein inhibitor 2 (Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]-) is an inhibitor of JAMM protease and can be used for anticancer studies. The IC50s are 10 μM, 46 μM, and 89 μM for thrombin, Rpn11, and MMP2, respectively.

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Pack Size	Price	Availability
1 mg	$116	In Stock
5 mg	$287	In Stock
10 mg	$497	In Stock
25 mg	$793	In Stock
50 mg	$1,130	In Stock
100 mg	$1,520	In Stock
500 mg	$2,970	In Stock
1 mL x 10 mM (in DMSO)	$398	In Stock

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Product Introduction

Bioactivity

Description	JAMM protein inhibitor 2 (Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]-) is an inhibitor of JAMM protease and can be used for anticancer studies. The IC50s are 10 μM, 46 μM, and 89 μM for thrombin, Rpn11, and MMP2, respectively.
Alias	Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]-

Chemical Properties

Molecular Weight	338.44
Formula	C21H26N2O2
Cas No.	848249-35-4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 4 mg/mL (11.82 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9547 mL	14.7737 mL	29.5473 mL	147.7367 mL
5 mM	0.5909 mL	2.9547 mL	5.9095 mL	29.5473 mL
10 mM	0.2955 mL	1.4774 mL	2.9547 mL	14.7737 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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Tech Support

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