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ADR-925
🥰Excellent
Catalog No. T29670Cas No. 75459-34-6
Alias ICRF-198, ICRF198, ICRF 198, ADR925, ADR 925
ADR-925, an active chelated iron metabolite of dexrazoxane, has the ability to protect neonatal rat cardiomyocytes from doxorubicin-induced injury.
ADR-925
🥰Excellent
Purity: 98%
Catalog No. T29670Alias ICRF-198, ICRF198, ICRF 198, ADR925, ADR 925Cas No. 75459-34-6
ADR-925, an active chelated iron metabolite of dexrazoxane, has the ability to protect neonatal rat cardiomyocytes from doxorubicin-induced injury.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $1,120 | In Stock | |
| 5 mg | $2,250 | In Stock | |
| 10 mg | $2,970 | In Stock | |
| 25 mg | $4,490 | In Stock | |
| 50 mg | $5,970 | In Stock |
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Purity:98%
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Product Introduction
Bioactivity
Chemical Properties
| Description | ADR-925, an active chelated iron metabolite of dexrazoxane, has the ability to protect neonatal rat cardiomyocytes from doxorubicin-induced injury. |
| In vivo | METHODS: ADR-925 (ICRF 198) (88 mg/kg, intraperitoneal injection, 30 minutes before doxorubicin injection, once a week, 12 times) was administered to mice to observe the protective effect of ADR-925 against the lethal effects of mice. RESULTS In animals pretreated with ADR559, there was partial protection against the lethal effects of doxorubicin. [2] |
| Alias | ICRF-198, ICRF198, ICRF 198, ADR925, ADR 925 |
| Molecular Weight | 304.3 |
| Formula | C11H20N4O6 |
| Cas No. | 75459-34-6 |
| Smiles | N([C@H](CN(CC(N)=O)CC(O)=O)C)(CC(N)=O)CC(O)=O |
| Relative Density. | 1.409 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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