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Afabicin is the prodrug of Debio1452. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,230 | 6-8 weeks | |
50 mg | $1,600 | 6-8 weeks | |
100 mg | $2,430 | 6-8 weeks |
Description | Afabicin is the prodrug of Debio1452. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci. |
In vitro | Debio1452 inhibits S. aureus, with MICs of ≤0.12 μg/mL and MIC50 and MIC90 values of 0.004 μg/mL and 0.008 μg/mL, respectively[1]. Debio1452 is highly active against staphylococci isolates, with MIC50 and MIC90 values of 0.015 μg/mL and 0.12 μg/mL, respectively. |
Alias | Debio 1450, AFN-1720 |
Molecular Weight | 485.43 |
Formula | C23H24N3O7P |
Cas No. | 1518800-35-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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