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ALS-8112

Catalog No. T14195Cas No. 1445379-92-9
Alias ALS 008112

ALS-8112 (ALS 008112) is a selective and potent inhibitor of respiratory syncytial virus (RSV) polymerase with an IC50 value of 0.02 μM. ALS-8112 exhibits antiviral activity and inhibits the RNA polymerase activity of the RSV L-P protein complex through RNA chain termination. virus infections.

ALS-8112

ALS-8112

Purity: 98.90%
Catalog No. T14195Alias ALS 008112Cas No. 1445379-92-9
ALS-8112 (ALS 008112) is a selective and potent inhibitor of respiratory syncytial virus (RSV) polymerase with an IC50 value of 0.02 μM. ALS-8112 exhibits antiviral activity and inhibits the RNA polymerase activity of the RSV L-P protein complex through RNA chain termination. virus infections.
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1 mg$139In Stock
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Purity:98.90%
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Product Introduction

Bioactivity
Description
ALS-8112 (ALS 008112) is a selective and potent inhibitor of respiratory syncytial virus (RSV) polymerase with an IC50 value of 0.02 μM. ALS-8112 exhibits antiviral activity and inhibits the RNA polymerase activity of the RSV L-P protein complex through RNA chain termination. virus infections.
Targets&IC50
RSV:0.02 μM
In vitro
ALS-8112 is an efficient nucleoside RSV polymerase inhibitor with an IC50 value of 0.02 μM.
AliasALS 008112
Chemical Properties
Molecular Weight293.68
FormulaC10H13ClFN3O4
Cas No.1445379-92-9
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 30 mg/mL (102.15 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.4051 mL17.0253 mL34.0507 mL170.2533 mL
5 mM0.6810 mL3.4051 mL6.8101 mL34.0507 mL
10 mM0.3405 mL1.7025 mL3.4051 mL17.0253 mL
20 mM0.1703 mL0.8513 mL1.7025 mL8.5127 mL
50 mM0.0681 mL0.3405 mL0.6810 mL3.4051 mL
100 mM0.0341 mL0.1703 mL0.3405 mL1.7025 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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