Shopping Cart
- Remove All
![TargetMol](https://newstatic.targetmol.com/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | Anti-inflammatory agent 48 functions by inhibiting the NF-κB signaling pathway and activating HO-1 expression, characterizing its role as an anti-inflammatory agent [1]. |
In vitro | Anti-inflammatory agent 48 (compound 1; 20 mg/kg) exhibited the capability to inhibit NO production in LPS-induced RAW 264.7 macrophages. Compared to Diclofenac, Anti-inflammatory agent 48 demonstrated superior inhibition of NF-κB by activating the Nrf2/HO-1 signaling pathway in RAW 264.7 cells [1]. |
In vivo | Anti-inflammatory agent 48 (compound 1; 20 mg/kg) significantly alleviated colitis in a dextran sulfate sodium (DSS)-induced mouse model by upregulating HO-1 and downregulating the phosphorylation levels of NF-κB p65 [1]. |
Molecular Weight | 442.33 |
Formula | C24H21Cl2NO3 |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.