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Avdoralimab
🥰Excellent
Catalog No. T76913Cas No. 2226393-85-5
Alias IPH5401, IPH 5401, Anti-C5aR1 mAb
Avdoralimab (IPH 5401) is a humanized monoclonal antibody targeting Complement C5a receptor 1 (C5aR1), used in research on bullous pemphigoid and chronic urticaria.
Avdoralimab
Avdoralimab
🥰Excellent
Catalog No. T76913Alias IPH5401, IPH 5401, Anti-C5aR1 mAbCas No. 2226393-85-5
Avdoralimab (IPH 5401) is a humanized monoclonal antibody targeting Complement C5a receptor 1 (C5aR1), used in research on bullous pemphigoid and chronic urticaria.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $263 | In Stock | |
| 5 mg | $795 | In Stock | |
| 10 mg | $1,260 | In Stock | |
| 25 mg | $1,870 | In Stock | |
| 50 mg | $2,520 | In Stock |
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Concentration:7.74 mg/mL
Purity:>95%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Avdoralimab (IPH 5401) is a humanized monoclonal antibody targeting Complement C5a receptor 1 (C5aR1), used in research on bullous pemphigoid and chronic urticaria. |
| In vitro | Avdoralimab is a whole-human IgG κb monoclonal antibody that targets the complement C5a receptor 1 (C5aR1), preventing it from binding to C5a. Improving the role of complement cascade in tumor biology by reducing the migration and activation of neutrophils and myeloid suppressor cells to the tumor microenvironment, and enhancing the antitumor activity of effector cells such as T cells and natural killer cells. [1] |
| In vivo | Avdoralimab blocked C5A-mediated recruitment and activation of human bone marrow cells and inhibited acute lung injury in human C5aR1 knockin mice. [2] |
| Alias | IPH5401, IPH 5401, Anti-C5aR1 mAb |
| Cas No. | 2226393-85-5 |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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