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BMS641

🥰Excellent
Catalog No. T26854Cas No. 369364-50-1
Alias BMS-641, BMS-209641, BMS 641

BMS641 (BMS-209641) is a selective and potent RARβ agonist with high affinity for RARβ, which synergistically activates RARβ and RARgamma to induce cellular maturation into specialized neuronal subtypes.

BMS641

BMS641

🥰Excellent
Purity: 98.98%
Catalog No. T26854Alias BMS-641, BMS-209641, BMS 641Cas No. 369364-50-1
BMS641 (BMS-209641) is a selective and potent RARβ agonist with high affinity for RARβ, which synergistically activates RARβ and RARgamma to induce cellular maturation into specialized neuronal subtypes.
Pack SizePriceAvailabilityQuantity
1 mg$159In Stock
5 mg$396In Stock
10 mg$662In Stock
25 mg$1,280In Stock
50 mg$1,830In Stock
100 mg$2,470In Stock
1 mL x 10 mM (in DMSO)$436In Stock
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Purity:98.98%
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Product Introduction

Bioactivity
Description
BMS641 (BMS-209641) is a selective and potent RARβ agonist with high affinity for RARβ, which synergistically activates RARβ and RARgamma to induce cellular maturation into specialized neuronal subtypes.
Targets&IC50
RARα:225 nM (Kd), RARβ:2.5 nM (Kd), RARγ:223 nM (Kd)
AliasBMS-641, BMS-209641, BMS 641
Chemical Properties
Molecular Weight414.92
FormulaC27H23ClO2
Cas No.369364-50-1
SmilesCC1(C)C=2C(C(=CC1)C3=CC=CC=C3)=CC(/C=C/C4=C(Cl)C=C(C(O)=O)C=C4)=CC2
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 5 mg/mL (12.05 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4101 mL12.0505 mL24.1010 mL120.5052 mL
5 mM0.4820 mL2.4101 mL4.8202 mL24.1010 mL
10 mM0.2410 mL1.2051 mL2.4101 mL12.0505 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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