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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $58 | In Stock | |
10 mg | $97 | In Stock | |
25 mg | $223 | In Stock | |
50 mg | $358 | In Stock | |
100 mg | $497 | In Stock | |
1 mL x 10 mM (in DMSO) | $58 | In Stock |
Description | BMS 753 is an agonist of isotype-selective retinoic acid receptor α (RARα, Ki= 2 nM). |
Targets&IC50 | RARα:2 nM (Ki) |
In vitro | In WT cells, BMS 753 can reduce RAR β Transcription level of 2 in a dose dependent mode. At RAR γ-/- cells, 100 nM of BMS 753 efficiently induces RAR β 2 Transcription. In contrast, in RAR α-/- In cells, up to 100 nM of BMS 753 can not activate RAR β 2[1]. |
Molecular Weight | 351.4 |
Formula | C21H21NO4 |
Cas No. | 215307-86-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45.0 mg/mL (128.1 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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