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BMS 753
Catalog No. T22049Cas No. 215307-86-1
BMS 753 is an agonist of isotype-selective retinoic acid receptor α (RARα, Ki= 2 nM).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $58 | In Stock | |
| 10 mg | $97 | In Stock | |
| 25 mg | $223 | In Stock | |
| 50 mg | $358 | In Stock | |
| 100 mg | $497 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $58 | In Stock |
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CitedProduct Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | BMS 753 is an agonist of isotype-selective retinoic acid receptor α (RARα, Ki= 2 nM). |
| Targets&IC50 | RARα:2 nM (Ki) |
| In vitro | In WT cells, BMS 753 can reduce RAR β Transcription level of 2 in a dose dependent mode. At RAR γ-/- cells, 100 nM of BMS 753 efficiently induces RAR β 2 Transcription. In contrast, in RAR α-/- In cells, up to 100 nM of BMS 753 can not activate RAR β 2[1]. |
| Molecular Weight | 351.4 |
| Formula | C21H21NO4 |
| Cas No. | 215307-86-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 45.0 mg/mL (128.1 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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