Shopping Cart
- Remove All
Your shopping cart is currently empty
BOS-318
🥰Excellent
Catalog No. T9964Cas No. 2387633-15-8
BOS-318 is a Furin inhibitor with IC50 of 1.9 nM, and has the characteristics of slow dissociation, high selectivity, and cell permeability.
BOS-318
🥰Excellent
Purity: 99.06%
Catalog No. T9964Cas No. 2387633-15-8
BOS-318 is a Furin inhibitor with IC50 of 1.9 nM, and has the characteristics of slow dissociation, high selectivity, and cell permeability.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $41 | In Stock | |
| 5 mg | $97 | In Stock | |
| 10 mg | $159 | In Stock | |
| 25 mg | $322 | In Stock | |
| 50 mg | $513 | In Stock | |
| 100 mg | $747 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $123 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreSelect Batch
Purity:99.06%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | BOS-318 is a Furin inhibitor with IC50 of 1.9 nM, and has the characteristics of slow dissociation, high selectivity, and cell permeability. |
| In vitro | METHODS: PEA and CuFi-1 cells were treated with BOS-318 (0.03, 0.1, 0.3, 1 μM, 72 hours) and PEA and cell viability was monitored to investigate the protective effect of BOS-318 against the toxic effects of bacterial toxins activated by Furin protein. RESULTS The cell viability of CuFi-1 cells treated with PEA was approximately 2% of the control level. A single 0.3 μM dose of BOS-318 significantly increased the cell viability of PEA-treated cells to approximately 88% of the control level. [1] |
| Molecular Weight | 571.5 |
| Formula | C28H32Cl2N6O3 |
| Cas No. | 2387633-15-8 |
| Smiles | CN1CCN(CC1)c1ncc(Oc2cc(CN3CCC(CC(O)=O)CC3)cc(n2)-c2cc(Cl)cc(Cl)c2)cn1 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 12.5 mg/mL (21.87 mM), Sonication is recommended.  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy BOS-318 | purchase BOS-318 | BOS-318 cost | order BOS-318 | BOS-318 chemical structure | BOS-318 in vitro | BOS-318 formula | BOS-318 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.