enac

Lenacapavir (GS-6207) is a potent capsid-targeting inhibitor of HIV replication. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells.

Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

Fenaclon (Fenaclonum) is an anticonvulsant. It is indicated for the treatment of epilepsy.

Afacifenacin (SMP-986) fumarate is an M3 muscarinic receptor-selective antagonist used in the study of ischemic heart disease, urinary incontinence and cystitis and other disorders.

Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2/M phase. Suprafenacine binds to microtubules and inhibits aggregation at the colchicine junction. Suprafenacine is selective for cancer cells, including drug-resistant cancer cells.

Eltenac (B78820) is a non-steroidal anti-inflammatory, COX inhibitor with analgesic activity.Eltenac inhibits COX-1 and COX-2 and is used in the study of Acute Respiratory Distress Syndrome (ARDS).

Phenacetin (Acetophenetidin) is a phenylacetamide that was formerly used in ANALGESICS but nephropathy and METHEMOGLOBINEMIA led to its withdrawal from the market.

BOS-318 is a Furin inhibitor with slowly dissociating, highly selective, and cell-pemeable characteristcs.

Marstenacisside F1, a polyoxypregnanoside derivative of Tenacigenin B with anti-inflammatory properties, has been isolated from Marsdenia tenacissima. It suppresses lipopolysaccharide-induced nitric oxide (NO) production in RAW 264.7 cells.

Avenaciolide is a water-insoluble fungal metabolite originally isolated from A. avenaceus. It inhibits glutamate transport in isolated rat liver mitochondria (Ki = 8 μM).

Butenachlor is a pesticide, specifically a selective, soil-applied herbicide used for control of grass and some broad-leaved weeds.

Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac . It is more soluble than diclofenac acid in isopropylmyristate. Diclofenac methyl ester does not permeate human epidermal membranes in vitro.

Avenacin A 1 is a biochemical.

Amfenac promotes apoptosis in ARPE-19 cell culture.

Tenacissoside F is a natural product of Marsdenia, Asclepiadaceae. The catalog number is TN5126 and the CAS number is 928151-78-4. Tenacissoside F can be used as a reference standard.

Saflufenacil is a uracil-based herbicide used to control annual broadleaf weeds in soybeans and corn.

Robenacoxib (Onsior) is a non-steroidal compound with strong selectivity for cyclooxygenase-2 and anti-inflammatory activity.

Tenacigenin B, a component of the plant Poria cocos, is identified as 3-O-β-Allopyranosyl-(1→4).

11α-O-Tigloyl-12β-O-acetyltenacigenin B, an ester derivative isolated from Garcinia cambogia (MTC), modulates the antitumor effects of Aurora-A in lymphoma through its parent compound, Tenacigenin B.

Tenacissoside I (Tenacissimoside B),Tenacissosides B, C and marsdenoside K inhibit the proliferation of Raji, NB4 and K562 cells in vitro significantly, in a dose and time dependent manner.

Lenacil (634 Hexilure) is an agent of herbicide.Lenacil can inhibit photosynthesis.

Aceclofenac methyl ester belongs to the aryl propionic acid derivatives

4'-Hydroxydiclofenac is a diclofenac metabolite.

Flufenacet is a herbicide, inhibiting very-long-chain fatty acid elongase (VLCFAE) synthesis.

Fenclofenac is a non-steroidal anti-inflammatory agent that competitively supresses the binding of thyroxine(T4) and triiodothyronine (T3) by thyroxine-binding globulin(TBG).

Tofenacin (free base) is an antidepressant drug with a tricyclic-like structure. It acts as a serotonin-norepinephrine reuptake inhibitor, and based on its close relation to orphenadrine, may also possess anticholinergic and antihistamine properties. Tofenacin is also the major active metabolite of orphenadrine and likely plays a role in its beneficial effects against depressive symptoms seen in Parkinson's disease patients.

Mefenacet is an herbicide for rice.

Pregabalin arenacarbil is a gabamimetic.

Phenacaine (Holocaine), a local anesthetic, suppresses the calmodulin-dependent activation of erythrocyte Ca2+-ATPase and inhibits cyclic nucleotide phosphodiesterases in the brain and heart, as evidenced by studies [1] [2].

Solifenacin succinate (YM905) is a quinuclidine and tetrahydroisoquinoline derivative and selective M3 MUSCARINIC ANTAGONIST. It is used as a UROLOGIC AGENT in the treatment of URINARY INCONTINENCE.

Imidafenacin (KRP-197)(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM.

Solifenacin (YM905 free base) (YM905 free base) is a novel muscarinic receptor antagonist, its pKis for M1, M2 and M3 receptors is of 7.6, 6.9 and 8.0, respectively.

Zamifenacin obviously decreases colonic motility in irritable bowel syndrome. Zamifenacin is an effective gut-selective muscarinic M3 receptor antagonist.

4’-Hydroxy Diclofenac-d4 (Major) is a deuterated compound of 4’-Hydroxy Diclofenac. 4’-Hydroxy Diclofenac has a CAS number of 64118-84-9. 4'-Hydroxydiclofenac is a diclofenac metabolite.

4’-Hydroxy Diclofenac-d4 is a deuterated compound of 4’-Hydroxy Diclofenac. 4’-Hydroxy Diclofenac has a CAS number of 64118-84-9. 4'-Hydroxydiclofenac is a diclofenac metabolite.

Imidafenacin-d10 is a deuterated compound of Imidafenacin. Imidafenacin has a CAS number of 170105-16-5. Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM.

Revefenacin (TD-4208) is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease.

Imidafenacin metabolite M4 is a metabolite of the muscarinic acetylcholine receptor antagonist imidafenacin.1It is formed from imidafenacin by the cytochrome P450 (CYP) isoform CYP3A4. 1.Kanayama, N., Kanari, C., Masuda, Y., et al.Drug-drug interactions in the metabolism of imidafenacin: Role of the human cytochrome P450 enzymes and UDP-glucuronic acid transferases, and potential of imidafenacin to inhibit human cytochrome P450 enzymesXenobiotica37(2)139-154(2007)

Butafenacil is an effective anemia inducer.

3-hydroxy Darifenacin is a metabolite of darifenacin . It is an antagonist of M1-5 muscarinic receptors (Kis = 17.78, 79.43, 2.24, 36.31, and 6.17 nM, respectively, in CHO cells).

11,12-Di-O-acetyltenacigenin B is a natural product for research related to life sciences. The catalog number is TN2577 and the CAS number is 857897-01-9.

Bromfenac Sodium (AHR 10282R) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.

Diclofenac Amide is used as a intermediates of Diclofenac.

Darifenacin hydrobromide (UK-88525) is a selective muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.

Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.

Methylbenactyzium Bromide (Semulgin) is an anticonvulsant that is the active metabolite of trimethadione.

Diclofenac (Diclofenacum) is a nonsteroidal benzeneacetic acid derivative with anti-inflammatory activity. Diclofenac binds and chelates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of arachidonic acid to pro-inflammatory-proprostaglandins.

Avenacoside A is a useful organic compound for research related to life sciences. The catalog number is T125207 and the CAS number is 24915-65-9.

N'-Phenacylpiperazineinnuchenenolide C is a useful organic compound for research related to life sciences and the catalog number is T131470.

Alclofenac sodium is an anti-inflammatory utilized in the treatment of rheumatoid arthritis.