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Solifenacin succinate (YM905) is a quinuclidine and tetrahydroisoquinoline derivative and selective M3 MUSCARINIC ANTAGONIST. It is used as a UROLOGIC AGENT in the treatment of URINARY INCONTINENCE.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $30 | In Stock | |
100 mg | $53 | In Stock | |
500 mg | $118 | In Stock | |
1 g | $173 | In Stock | |
1 mL x 10 mM (in DMSO) | $29 | In Stock |
Description | Solifenacin succinate (YM905) is a quinuclidine and tetrahydroisoquinoline derivative and selective M3 MUSCARINIC ANTAGONIST. It is used as a UROLOGIC AGENT in the treatment of URINARY INCONTINENCE. |
In vivo | Solifenacin succinate is a novel muscarinic antagonist indicated for the treatment of overactive bladder syndrome. When co-administered with oxybutynin, Solifenacin effectively inhibits the mobilization of intracellular calcium mediated by muscarinic M3 receptors in isolated bladder smooth muscle cells of guinea pigs and submandibular gland cells of mice. |
Alias | YM905 |
Molecular Weight | 480.56 |
Formula | C23H26N2O2·C4H6O4 |
Cas No. | 242478-38-2 |
Smiles | O(C(=O)N1[C@H](c2c(CC1)cccc2)c1ccccc1)[C@@H]1C2CCN(C1)CC2.O=C(O)CCC(=O)O |
Relative Density. | 1.24g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 25 mg/mL (52.02 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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