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Solifenacin succinate

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Purity:99.73%

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COA HNMR HPLC

Solifenacin succinate

Catalog No. T0111Cas No. 242478-38-2

Solifenacin succinate (YM905) is a quinuclidine and tetrahydroisoquinoline derivative and selective M3 MUSCARINIC ANTAGONIST. It is used as a UROLOGIC AGENT in the treatment of URINARY INCONTINENCE.

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Pack Size	Price	Availability
25 mg	$33	In Stock
50 mg	$47	In Stock
100 mg	$89	In Stock
200 mg	$121	In Stock
500 mg	$196	In Stock
1 g	$289	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Product Introduction

Bioactivity

Description	Solifenacin succinate (YM905) is a quinuclidine and tetrahydroisoquinoline derivative and selective M3 MUSCARINIC ANTAGONIST. It is used as a UROLOGIC AGENT in the treatment of URINARY INCONTINENCE.
In vivo	Solifenacin succinate is a novel muscarinic antagonist indicated for the treatment of overactive bladder syndrome. When co-administered with oxybutynin, Solifenacin effectively inhibits the mobilization of intracellular calcium mediated by muscarinic M3 receptors in isolated bladder smooth muscle cells of guinea pigs and submandibular gland cells of mice.
Alias	YM905

Chemical Properties

Molecular Weight	480.56
Formula	C23H26N2O2·C4H6O4
Cas No.	242478-38-2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 25 mg/mL (52.02 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0809 mL	10.4045 mL	20.8091 mL	104.0453 mL
5 mM	0.4162 mL	2.0809 mL	4.1618 mL	20.8091 mL
10 mM	0.2081 mL	1.0405 mL	2.0809 mL	10.4045 mL
20 mM	0.1040 mL	0.5202 mL	1.0405 mL	5.2023 mL
50 mM	0.0416 mL	0.2081 mL	0.4162 mL	2.0809 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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