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Chelidonine hydrochloride

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Purity:100%

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COA HPLC HNMR

Chelidonine hydrochloride

Catalog No. T7324Cas No. 4312-31-6

Chelidonine hydrochloride is one of the alkaloids of Chelidonium majus, which has broad pharmacological activities

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Pack Size	Price	Availability
1 mg	$78	In Stock
5 mg	$183	In Stock
50 mg	$668	Backorder

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Questions

Related Compound Libraries of "Chelidonine hydrochloride"

Product Introduction

Bioactivity

Description

Chelidonine hydrochloride is one of the alkaloids of Chelidonium majus, which has broad pharmacological activities

In vitro

Chelidonine significantly suppressed LPS-induced the production of NO and PGE2, as well as iNOS and COX-2 mRNA and protein expression.?In addition, pro-inflammatory cytokines induced by LPS, such as TNFα and IL-6 were also attenuated by chelidonine.?What's more, LPS-induced activation and degradation of IκBα followed by translocation of the p65 from the cytoplasm to the nucleus were attenuated by chelidonine.?Furthermore, chelidonine even significantly inhibited TLR4 expression induced by LPS[1].

Chemical Properties

Molecular Weight	389.83
Formula	C20H20ClNO5
Cas No.	4312-31-6

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: <10 mM

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5652 mL	12.8261 mL	25.6522 mL	128.2610 mL
5 mM	0.5130 mL	2.5652 mL	5.1304 mL	25.6522 mL
10 mM	0.2565 mL	1.2826 mL	2.5652 mL	12.8261 mL

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In Vivo Formulation Calculator (Clear solution)

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Keywords

Chelidonine HydrochlorideChelidonine hydrochloride