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CQ211 is a potent and selective RIOK2 inhibitor with a Kd of 6.1 nM, demonstrating significant proliferation inhibitory activity against various cancer cell lines in vitro.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $71 | In Stock | |
5 mg | $172 | In Stock | |
10 mg | $259 | In Stock | |
25 mg | $469 | In Stock | |
50 mg | $689 | In Stock | |
100 mg | $1,015 | In Stock | |
1 mL x 10 mM (in DMSO) | $197 | In Stock |
Description | CQ211 is a potent and selective RIOK2 inhibitor with a Kd of 6.1 nM, demonstrating significant proliferation inhibitory activity against various cancer cell lines in vitro. |
Targets&IC50 | RIOK2:6.1 nM(Kd) |
In vivo | CQ211 (25 mg/kg; rat) inhibits the tumor progression with tumor growth inhibition (TGI) of 30.9%.[1] |
Molecular Weight | 521.49 |
Formula | C26H22F3N7O2 |
Cas No. | 2648986-65-4 |
Smiles | O=C1C2=C(C=3C(N1)=CC=C(C3)C=4C=CC(OC)=NC4)N(N=N2)C5=CC(C(F)(F)F)=C(C=C5)N6CCNCC6 |
Relative Density. | 1.52 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 6.25 mg/mL (11.98 mM), Sonication is recommended. ![]() | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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