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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $30 | 8-10 weeks |
Description | Dihomo-γ-linolenic acid (DGLA) is a fatty acid widely found in plants with antitumor and antiproliferative effects, inhibits the growth of xenograft tumor cells, and can be used in the study of inflammation-related diseases such as rheumatoid arthritis, atherosclerosis, and atopic dermatitis. |
In vitro | In THP-1 macrophages, Dihomo-γ-linolenic acid (50 μM; 24 hours) attenuates IFN-γ-induced phosphorylation of STAT1 at serine 727[2]. |
In vivo | In 48 four-week-old female nude mice, administration of 8 mg per mouse via oral gavage twice a week for 35 days suppressed the metastatic potential of D5D-KD tumors[3]. |
Alias | Diroleuton, all-cis-8,11,14-Eicosatrienoic acid, Ro 12-1989 |
Molecular Weight | 306.48 |
Formula | C20H34O2 |
Cas No. | 1783-84-2 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80 mg/mL (261.03 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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