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Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 mg | $41 | In Stock | |
1 mL x 10 mM (in DMSO) | $45 | In Stock |
Description | Dihydroxyfumaric acid is a known generator of superoxide anions and by hydroxyl free radicals. Dihydroxyfumarate exposure can cause insulin inhibitory effects. It can spontaneously convert to hydroxypyruvate or to oxaloglycolate. |
In vivo | Corynoxine promotes the formation of autophagosomes in the fat bodies of Drosophila. By inducing autophagy, Corynoxine promotes the clearance of wild-type and A53T α-syn in inducible PC12 cells. Corynoxine induces autophagy through the Akt/mTOR pathway as evidenced by the reduction in the levels of phospho-Akt, phospho-mTOR and phospho-p70 S6 Kinase [1]. Corynoxine significantly decreased locomotor activity after oral administration to mice [2]. |
Molecular Weight | 166.09 |
Formula | C4H6O7 |
Cas No. | 199926-38-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 55 mg/mL (331.16 mM) ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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