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DNA2 inhibitor C5

DNA2 inhibitor C5
DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM). DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2.
Catalog No. T15146Cas No. 35973-25-2
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Purity:98.00%
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DNA2 inhibitor C5

Catalog No. T15146Cas No. 35973-25-2

DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM). DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$55In Stock
2 mg$77In Stock
5 mg$122In Stock
10 mg$198In Stock
25 mg$455In Stock
50 mg$672In Stock
100 mg$956In Stock
500 mg$1,920In Stock
1 mL x 10 mM (in DMSO)$121In Stock
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Product Introduction

Bioactivity
Description
DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM). DNA2 inhibitor C5 inhibits nuclea
Targets&IC50
DNA2 nuclease:20 μM
Chemical Properties
Molecular Weight234.16
FormulaC10H6N2O5
Cas No.35973-25-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 31.25 mg/mL (133.45 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.2706 mL21.3529 mL42.7058 mL213.5292 mL
5 mM0.8541 mL4.2706 mL8.5412 mL42.7058 mL
10 mM0.4271 mL2.1353 mL4.2706 mL21.3529 mL
20 mM0.2135 mL1.0676 mL2.1353 mL10.6765 mL
50 mM0.0854 mL0.4271 mL0.8541 mL4.2706 mL
100 mM0.0427 mL0.2135 mL0.4271 mL2.1353 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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