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Pomalidomide-PEG4-Ph-NH2

🥰Excellent
Catalog No. T7756Cas No. 1818885-63-0

Pomalidomide-PEG4-Ph-NH2 is a synthetic E3 ligase ligand-linker conjugate that integrates a Pomalidomide-based cereblon ligand with a 4-unit PEG linker.

Pomalidomide-PEG4-Ph-NH2

Pomalidomide-PEG4-Ph-NH2

🥰Excellent
Purity: 99.49%
Catalog No. T7756Cas No. 1818885-63-0
Pomalidomide-PEG4-Ph-NH2 is a synthetic E3 ligase ligand-linker conjugate that integrates a Pomalidomide-based cereblon ligand with a 4-unit PEG linker.
Pack SizePriceAvailabilityQuantity
5 mg$30In Stock
10 mg$44In Stock
25 mg$71In Stock
50 mg$107In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:99.49%
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Product Introduction

Bioactivity
Description
Pomalidomide-PEG4-Ph-NH2 is a synthetic E3 ligase ligand-linker conjugate that integrates a Pomalidomide-based cereblon ligand with a 4-unit PEG linker.
Chemical Properties
Molecular Weight540.57
FormulaC27H32N4O8
Cas No.1818885-63-0
SmilesO=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCOCCOCCOCCOC4=CC=C(N)C=C4
Relative Density.1.363 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (92.49 mM)
H2O: < 0.1 mg/mL (insoluble)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8499 mL9.2495 mL18.4990 mL92.4950 mL
5 mM0.3700 mL1.8499 mL3.6998 mL18.4990 mL
10 mM0.1850 mL0.9249 mL1.8499 mL9.2495 mL
20 mM0.0925 mL0.4625 mL0.9249 mL4.6247 mL
50 mM0.0370 mL0.1850 mL0.3700 mL1.8499 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Dose Conversion

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