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Eltoprazine dihydrochloride

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Catalog No. T7746Cas No. 143485-51-2

Eltoprazine dihydrochloride is a drug that had previously been developed for aggression, has recently been investigated for L-DOPA-induced dyskinesia in animal models of Parkinson′s disease (PD) and in dyskinetic PD patients.

Eltoprazine dihydrochloride

Eltoprazine dihydrochloride

🥰Excellent
Purity: 99.94%
Catalog No. T7746Cas No. 143485-51-2
Eltoprazine dihydrochloride is a drug that had previously been developed for aggression, has recently been investigated for L-DOPA-induced dyskinesia in animal models of Parkinson′s disease (PD) and in dyskinetic PD patients.
Pack SizePriceAvailabilityQuantity
5 mg$48In Stock
10 mg$71In Stock
25 mg$127In Stock
50 mg$191In Stock
100 mg$288In Stock
1 mL x 10 mM (in DMSO)$63In Stock
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Purity:99.94%
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Product Introduction

Bioactivity
Description
Eltoprazine dihydrochloride is a drug that had previously been developed for aggression, has recently been investigated for L-DOPA-induced dyskinesia in animal models of Parkinson´s disease (PD) and in dyskinetic PD patients.
In vitro
In the elevated plus maze eltoprazine increased anxiety?like behavior.?On the other hand, it induced a clear?cut anxiolytic effect in context fear conditioning test starting at ca. 0.3 mg/kg[1]
Chemical Properties
Molecular Weight293.19
FormulaC12H18Cl2N2O2
Cas No.143485-51-2
SmilesCl.Cl.c1cc2c(c(N3CCNCC3)c1)OCCO2
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 10 mg/mL (34.11 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.4108 mL17.0538 mL34.1076 mL170.5379 mL
5 mM0.6822 mL3.4108 mL6.8215 mL34.1076 mL
10 mM0.3411 mL1.7054 mL3.4108 mL17.0538 mL
20 mM0.1705 mL0.8527 mL1.7054 mL8.5269 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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