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ERB-196
🥰Excellent
Catalog No. T11222Cas No. 550997-55-2
Alias WAY-202196
Erb-196 is an estrogen receptor-receptor agonist with non-steroidal selectivity.
ERB-196
🥰Excellent
Catalog No. T11222Alias WAY-202196Cas No. 550997-55-2
Erb-196 is an estrogen receptor-receptor agonist with non-steroidal selectivity.
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Product Introduction
Bioactivity
Chemical Properties
| Description | Erb-196 is an estrogen receptor-receptor agonist with non-steroidal selectivity. |
| In vivo | ERB-196 significantly reduces histopathologic evidence of injury to the gastrointestinal mucosal surface (0.7±0.1 vs. 2.3±0.2 for control;?p<0.05).?The mucosal mass of 10-cm segments of small bowel mucosa shows better preservation of mucosal mass than control treatment (63±20 [ERB-196] vs. 31±24 [control]), but this difference fails to reach statistical significance (p<0.06).?The administration of ERB-196 is highly effective in the prevention of lethality.?Consistent with the neutropenic rat model, ERB-196 significantly increases survival when compare with vehicle control. |
| Alias | WAY-202196 |
| Molecular Weight | 279.27 |
| Formula | C17H10FNO2 |
| Cas No. | 550997-55-2 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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