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Product Introduction

Bioactivity

Description	Erythorbic Acid (D-(-)-Isoascorbic acid) is an antiscorbutic agent
In vivo	Iron absorption from the test meal without any added enhancer was 4.1%. The addition of erythorbic acid (at molar ratios of 2:1 and 4:1 relative to iron) increased iron absorption 2.6-fold (10.8%; P < 0.0001) and 4.6-fold (18.8%; P < 0.0001), respectively. The addition of ascorbic acid (molar ratio of 4:1) increased iron absorption 2.9-fold (11.7%; P = 0.0004). At a molar ratio of 4:1, erythorbic acid was 1.6-fold (P = 0.0002) as potent an enhancer of iron absorption as was ascorbic acid.
Alias	D-(-)-Isoascorbic acid

Chemical Properties

Molecular Weight	176.12
Formula	C₆H₈O₆
Cas No.	89-65-6
Smiles	OCC(O)C1OC(=O)C(O)=C1O
Relative Density.	1 707 kg/m3. Temperature:20 °C.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 27.5 mg/mL (156.14 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.6779 mL	28.3897 mL	56.7795 mL	283.8973 mL
5 mM	1.1356 mL	5.6779 mL	11.3559 mL	56.7795 mL
10 mM	0.5678 mL	2.8390 mL	5.6779 mL	28.3897 mL
20 mM	0.2839 mL	1.4195 mL	2.8390 mL	14.1949 mL
50 mM	0.1136 mL	0.5678 mL	1.1356 mL	5.6779 mL
100 mM	0.0568 mL	0.2839 mL	0.5678 mL	2.8390 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

InhibitorinhibitfoodErythorbic AcidD-Isoascorbic acidD-Araboascorbic acidadditive