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Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol
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Catalog No. T87725Cas No. 2891774-71-1
Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol (compound 45), a camptothecin derivative, demonstrates potent inhibitory effects on cell proliferation, exhibiting an IC 50 of 2.92 ng/mL against MDA-MB-468 cells. It is primarily utilized in cancer research [1].
![Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol](/group3/M00/38/30/CgoaEWa8j22EQJ64AAAAAEfFEvo992.png)
Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol
😃Good
Catalog No. T87725Cas No. 2891774-71-1
Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol (compound 45), a camptothecin derivative, demonstrates potent inhibitory effects on cell proliferation, exhibiting an IC 50 of 2.92 ng/mL against MDA-MB-468 cells. It is primarily utilized in cancer research [1].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol (compound 45), a camptothecin derivative, demonstrates potent inhibitory effects on cell proliferation, exhibiting an IC 50 of 2.92 ng/mL against MDA-MB-468 cells. It is primarily utilized in cancer research [1]. |
| In vitro | Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol (compound 45) has an IC 50 value of 2.92 ng/mL in inhibiting the proliferation of MDA‑MB‑468 cells [1]. |
| Molecular Weight | 559.58 |
| Formula | C31H30FN3O6 |
| Cas No. | 2891774-71-1 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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