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GAT211

🥰Excellent
Catalog No. T27405Cas No. 102704-40-5
Alias GAT-211, GAT 211, AZ-4, AZ4, AZ 4

GAT211 (AZ-4) is a selective and potent cannabinoid 1 receptor (CB1R) orthosteric modulator (PAM) with high affinity for cAMP and β-arrestin2.GAT211 has IOP-lowering and antipsychotic effects and can be used in the study of epilepsy.

GAT211

GAT211

🥰Excellent
Purity: 99.7%
Catalog No. T27405Alias GAT-211, GAT 211, AZ-4, AZ4, AZ 4Cas No. 102704-40-5
GAT211 (AZ-4) is a selective and potent cannabinoid 1 receptor (CB1R) orthosteric modulator (PAM) with high affinity for cAMP and β-arrestin2.GAT211 has IOP-lowering and antipsychotic effects and can be used in the study of epilepsy.
Pack SizePriceAvailabilityQuantity
1 mg$30In Stock
5 mg$64In Stock
10 mg$97In Stock
25 mg$159In Stock
50 mg$233In Stock
100 mg$345In Stock
500 mg$833In Stock
1 mL x 10 mM (in DMSO)$71In Stock
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Purity:99.7%
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Product Introduction

Bioactivity
Description
GAT211 (AZ-4) is a selective and potent cannabinoid 1 receptor (CB1R) orthosteric modulator (PAM) with high affinity for cAMP and β-arrestin2.GAT211 has IOP-lowering and antipsychotic effects and can be used in the study of epilepsy.
In vitro
GAT211 limits dopamine D2 receptor-mediated extracellular signal-regulated kinase (ERK) phosphorylation in Neuro2a cells, while THC does not[2].
In vivo
When administered alone, GAT211 treatment (0.3-3.0 mg/kg) dose-dependently reduces locomotor activity and acoustic startle response. GAT211 (3.0 mg/kg) also prevents MK-801-induced hyperlocomotion but has no significant effect on PPI impairment[2].
AliasGAT-211, GAT 211, AZ-4, AZ4, AZ 4
Chemical Properties
Molecular Weight342.39
FormulaC22H18N2O2
Cas No.102704-40-5
Smiles[O-][N+](=O)CC(c1c([nH]c2ccccc12)-c1ccccc1)c1ccccc1
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (233.65 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9206 mL14.6032 mL29.2065 mL146.0323 mL
5 mM0.5841 mL2.9206 mL5.8413 mL29.2065 mL
10 mM0.2921 mL1.4603 mL2.9206 mL14.6032 mL
20 mM0.1460 mL0.7302 mL1.4603 mL7.3016 mL
50 mM0.0584 mL0.2921 mL0.5841 mL2.9206 mL
100 mM0.0292 mL0.1460 mL0.2921 mL1.4603 mL

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